Pyroglutamic acidosis caused by the combination of two common medicines prescribed in everyday practice

被引:0
|
作者
Duncan, A. [1 ,2 ,4 ]
McDermott, H. [1 ,2 ]
Corcoran, S. [1 ,2 ]
Devine, C. [1 ,2 ,3 ]
Barry, C. [1 ,2 ]
机构
[1] Bon Secours Hosp, Dept Med, Dublin, Ireland
[2] Bon Secours, Dept Microbiol, Dublin, Ireland
[3] Bon Secours, Dept Pharm, Dublin, Ireland
[4] Bon Secours, Gen Internal Med, Dublin, Ireland
来源
OXFORD MEDICAL CASE REPORTS | 2023年 / 2023卷 / 05期
关键词
D O I
10.1093/omcr/omad048
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We present the case of a 71-year-old female treated for infective endocarditis with flucloxacillin and paracetamol. Her clinical course became complicated by a blood-gas demonstrating a raised anion gap metabolic acidosis. The patient was diagnosed with pyroglutamic metabolic acidosis. This is a rare interaction between high dose flucloxacillin and paracetamol, and is an important complication to recognize.
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页数:2
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