Current Advances in Wound Healing and Regenerative Medicine

被引:2
|
作者
Fani, Nesa [1 ]
Moradi, Maryam [2 ]
Zavari, Roxana [3 ]
Parvizpour, Farzad [3 ,4 ]
Soltani, Adele [5 ,6 ]
Arabpour, Zohreh [3 ]
Jafarian, Arefeh [3 ]
机构
[1] ACECR, Royan Inst Stem Cell Biol & Technol, Cell Sci Res Ctr, Dept Stem Cells & Dev Biol, Tehran, Iran
[2] MD MPH Iran Univ Med Sci, Tehran, Iran
[3] Univ Tehran Med Sci, Cell & Tissue Inst, Iranian Tissue Bank & Res Ctr, Gene, Tehran, Iran
[4] Kurdistan Univ Med Sci, Fac Med, Dept Mol Med, Sanandaj, Iran
[5] Alborz Univ Med Sci, CinnaGen Med Biotechnol Res Ctr, Karaj, Iran
[6] CinnaGen Res & Prod Co, Alborz, Iran
关键词
Chronic wounds; natural polymers; peptides; cytokines; RNA interference; gene therapy; MESENCHYMAL STEM-CELLS; TISSUE-BASED PRODUCTS; GROWTH-FACTORS; STROMAL CELLS; GENE-THERAPY; IN-VITRO; SKIN; CARE; FIBROBLASTS; PHYSIOLOGY;
D O I
10.2174/1574888X18666230301140659
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Treating chronic wounds is a common and costly challenge worldwide. More advanced treatments are needed to improve wound healing and prevent severe complications such as infection and amputation. Like other medical fields, there have been advances in new technologies promoting wound healing potential.Regenerative medicine as a new method has aroused hope in treating chronic wounds. The technology improving wound healing includes using customizable matrices based on synthetic and natural polymers, different types of autologous and allogeneic cells at different differentiation phases, small molecules, peptides, and proteins as a growth factor, RNA interference, and gene therapy. In the last decade, various types of wound dressings have been designed. Emerging dressings include a variety of interactive/bioactive dressings and tissue-engineering skin options. However, there is still no suitable and effective dressing to treat all chronic wounds.This article reviews different wounds and common treatments, advanced technologies and wound dressings, the advanced wound care market, and some interactive/bioactive wound dressings in the market.
引用
收藏
页码:277 / 291
页数:15
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