Relationship Between the Visceral Adiposity Index and Peyronie's Disease

Objective: We aimed to investigate the relationship between Peyronie's disease (PD) and the visceral adiposity index (VAI), which is thought to predict visceral obesity homogeneously.Materials and Methods: We included 102 healthy volunteers (Group 1) and 89 patients with PD (Group 2) in this retrospective study. We recorded demographic, anthropometric, and clinical data, including age, comorbidity, International Index of Erectile Function (IIEF) score, waist circumference (WC), body mass index (BMI), visceral adiposity index testosterone (VAI), serum fasting glucose, high-density lipoprotein (HDL), and triglyceride (TG). For Group 2 participants, plaque size, duration of symptoms, and degree of penile curvature were recorded.Results: The mean ages of Group 1 and Group 2 were 55.12 +/- 9.51 years and 54.79 +/- 9.99 years, respectively (p>0.05). The mean BMI, WC, VAI, fasting glucose, and TG values were significantly higher in Group 2 (p<0.001, p=0.004, p=0.001, p=0.001, and p=0.003, respectively). The mean HDL values between the groups were similar (p>0.05). The mean IIEF score was lower in Group 2 than in Group 1 (p=0.008). An increase of 1 unit in the VAI value increases the probability of having PD 1.2 times (p=0.001). Each VAI integer increase decreased 1.25 points in the IIEF score, a 1 mm increase in plaque size, and a 1.98-degree increase in curvature.Conclusion: Our study has shown that VAI can be used as a reliable, independent risk factor for plaque size and penile curvature in patients with patients with PD.