Exosomes as biomarkers and therapeutic measures for ischemic stroke

被引：0
|
作者：
Shi, Yun [1 ]
Wang, Ruirui [1 ]
Wang, Lei [1 ,2 ,3 ,4 ]
Liu, Qing [1 ]
Han, Lan [1 ,2 ]
Duan, Xianchun [1 ]
Zhang, Yanchun [1 ]
Shen, Aizong [5 ]
Peng, Daiyin [1 ,2 ,4 ,6 ]
Chen, Weidong [1 ,2 ,4 ,6 ,7 ]
Ji, Zhaojie [1 ]
机构：
[1] Anhui Univ Chinese Med, Coll Pharm, Hefei 230012, Peoples R China
[2] MOE, Anhui Joint Collaborat Innovat Ctr Qual Improvemen, Hefei, Peoples R China
[3] Anhui Acad Chinese Med, Inst Pharmaceut, Hefei, Peoples R China
[4] Anhui Prov Key Lab Chinese Med Formula, Hefei, Peoples R China
[5] Univ Sci & Technol China, Affiliated Hosp USTC 1, Dept Pharm, Div Life Sci & Med, Hefei, Peoples R China
[6] Inst Tradit Chinese Med Resources Protect & Dev, Hefei, Peoples R China
[7] Anhui Prov Key Lab Tradit Chinese Med Decoct Piece, Hefei, Peoples R China
来源：
EUROPEAN JOURNAL OF PHARMACOLOGY | 2023年 / 939卷
基金：
中国国家自然科学基金;
关键词：
Exosomes; Ischemic stroke; Biomarkers; Therapeutic measures; CELL-DERIVED EXOSOMES; NEURAL STEM-CELLS; EXTRACELLULAR VESICLES; FUNCTIONAL RECOVERY; CIRCULATING MICRORNAS; REPERFUSION INJURY; DELIVERY-SYSTEMS; MOUSE-BRAIN; PROTECT; DISEASE;
D O I：
10.1016/j.ejphar.2022.175477
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Ischemic stroke (IS) is the leading cause of long-term disability in the world and characterized by high morbidity, recurrence, complications, and mortality. Due to the lack of early diagnostic indicators, limited therapeutic measures and inadequate prognostic indicators, the diagnosis and treatment of IS remains a particular challenge at present. It has recently been reported that exosomes (EXOs) play a significant role in the pathogenesis and treatment of IS. The purpose of this paper is to probe the role of EXOs in diagnostic biomarkers and therapeutic measures for IS and to provide innovative ideas for improving the prognosis of IS.
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页数：12
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