Quantifying Corneal Topographic Astigmatism (CorT Total) in Keratoconic Eyes

PURPOSE: To determine optimal corneal regions from which to derive corneal topographic astigmatism (CorT) in keratoconic eyes. METHODS: In this retrospective study, potential measures of corneal astigmatism are calculated from raw total corneal power data (179 eyes from 124 patients) from a corneal tomographer. The measures are derived from annular corneal regions varying in both extent and center position, and evaluated according to the variability of the ocular residual astigmatism ( ORA) in the cohort. This variability is quantified by the ORArms, which is the root-mean-squared distance of the ORAs from their summated vector mean in double angle space. The lower the ORArms, the better the corneal astigmatism measure corresponds to manifest refractive cylinder. RESULTS: Corneal astigmatism measures derived from regions centered on corneal vertex had ORArms values (mild: 1.07 diopters [D], moderate: 1.61 D, severe: 2.65 D) as low or lower than other measures derived from regions centered on thinnest point, corneal apex (front or back), or pupil center. Corneal astigmatism measures derived from a region centered 30% of the way toward thinnest point from corneal vertex appeared to have even lower ORArms values (mild: 1.05 D, moderate: 1.45 D, severe: 2.56 D). None of the corneal astigmatism measures corresponded closely with manifest refractive cylinder for severe keratoconus (ORArms > 2.50 D). CONCLUSIONS: For keratoconic eyes, the CorT should be derived from an annular region centered 30% of the way toward thinnest point from corneal vertex, although when the keratoconus is mild, a standard corneal-vertex-centered CorT performs just as well.