Visible-Light-Mediated Bimetal-Catalyzed meta-Alkylation of Arenes

被引：7
|
作者：
Cui, Peng-Cheng [1 ,2 ]
Wang, Guan-Wu [1 ,2 ,3 ]
机构：
[1] Univ Sci & Technol China, Hefei Natl Res Ctr Phys Sci Microscale, Hefei 230026, Anhui, Peoples R China
[2] Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
[3] Lanzhou Univ, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 02期
关键词：
C-H FUNCTIONALIZATION; ACTIVATION;
D O I：
10.1021/acs.orglett.3c03266
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A mild approach to the visible-light-mediated bimetal-catalyzed meta-alkylation of arenes has been accomplished. The regioselective meta-alkylation is realized by a bimetallic ruthenium-palladium system. Ruthenium acts as a catalyst for the directing effect and as a photosensitizer, while the cocatalyst palladium behaves as a catalyst for the generation of fluoroalkyl radicals. This reaction not only is suitable for two-component meta-fluoroalkylation of arenes but can also be extended to three-component reactions to achieve bifunctionalization of olefins.
引用
收藏
页码：427 / 432
页数：6
相关论文
共 50 条
  • [1] Visible-Light-Mediated Synthesis of Trifluoromethylthiolated Arenes
    Ghiazza, Clement
    Monnereau, Cyrille
    Khrouz, Lhoussain
    Billard, Thierry
    Tlili, Anis
    SYNTHESIS-STUTTGART, 2019, 51 (14): : 2865 - 2870
  • [2] Visible-light-mediated aerobic selenation of (hetero)arenes with diselenides
    Zhang, Qing-Bao
    Ban, Yong-Liang
    Yuan, Pan-Feng
    Peng, Shou-Jiao
    Fang, Jian-Guo
    Wu, Li-Zhu
    Liu, Qiang
    GREEN CHEMISTRY, 2017, 19 (23) : 5559 - 5563
  • [3] Visible-Light-Mediated Ruthenium-Catalyzed para-Selective Alkylation of Unprotected Anilines
    Lv, Xinyan
    Cheng, Yaohang
    Zong, Yingxiao
    Wang, Qingyun
    An, Guanghui
    Wang, Junke
    Li, Guangming
    ACS CATALYSIS, 2023, 13 (11) : 7310 - 7321
  • [4] Visible-Light-Mediated Synthesis of Ketones by the Oxidative Alkylation of Styrenes
    Tlahuext-Aca, Adrian
    Garza-Sanchez, R. Aleyda
    Schaefer, Michael
    Glorius, Frank
    ORGANIC LETTERS, 2018, 20 (06) : 1546 - 1549
  • [5] Visible-Light-Mediated Cyclopropanation Reactions of 3-Diazooxindoles with Arenes
    Zhao, Shuai
    Chen, Xiang-Xiang
    Gao, Nan
    Qian, Mingcheng
    Chen, Xin
    JOURNAL OF ORGANIC CHEMISTRY, 2021, 86 (10): : 7131 - 7140
  • [6] Visible-Light-Mediated Metal-Free Synthesis of Trifluoromethylselenolated Arenes
    Ghiazza, Clement
    Debrauwer, Vincent
    Monnereau, Cyrille
    Khrouz, Lhoussain
    Medebielle, Maurice
    Billard, Thierry
    Tlili, Anis
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2018, 57 (36) : 11781 - 11785
  • [7] Norcaradiene Synthesis via Visible-Light-Mediated Cyclopropanation Reactions of Arenes
    Guo, Yujing
    Thanh Vinh Nguyen
    Koenigs, Rene M.
    ORGANIC LETTERS, 2019, 21 (21) : 8814 - 8818
  • [8] Visible-Light-Mediated C-H Alkylation of Pyridine Derivatives
    Rammal, Fatima
    Gao, Di
    Boujnah, Sondes
    Gaumont, Annie Claude
    Hussein, Aqeel A.
    Lakhdar, Sami
    ORGANIC LETTERS, 2020, 22 (19) : 7671 - 7675
  • [9] Visible-Light-Mediated Copper(I)-Catalyzed Regiospecific Amino-Hydroxylation and Amino-Alkoxylation of Vinyl Arenes
    Singh, Baldau
    Brijbhushan, Tiwari Neeraj
    Kumar, Krishn
    Pandey, Piyush
    Ganapathy, Dhandapani
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2025, 28 (01)
  • [10] Visible-Light-Mediated Direct Amidation of Arenes and Heteroarenes with N-Aminopyridinium Salts
    Xia, Cencen
    Hao, Xinyu
    Jin, Kun
    Zhang, Rong
    Duan, Chunying
    Li, Yaming
    SYNLETT, 2022, 33 (15) : 1551 - 1555
12345