Metal-free synthesis of 1,3-dichloro-1,5-diarylpentan-5-ones via cascade oxidative radical addition of styrenes with CHCl3

被引：0

作者：

Liu, Min ^{[1
,2
]}

Liu, Bifu ^{[1
,2
]}

Wang, Qian ^{[1
]}

Feng, Kejun ^{[1
]}

Li, Yuanhua ^{[1
]}

Liu, Lixin ^{[1
]}

Tong, Jiaen ^{[1
]}

机构：

[1] Huizhou Univ, Sch Chem & Mat Engn, Huizhou 516007, Peoples R China

[2] Huizhou Univ, Guangdong Prov Key Lab Elect Funct Mat & Devices, Huizhou 516001, Guangdong, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2024年 / 22卷 / 04期

基金：

中国国家自然科学基金;

关键词：

ALKENES; DIFUNCTIONALIZATION; FUNCTIONALIZATION; CHLORINATION; ACCESS; ROUTE;

D O I：

10.1039/d3ob01403g

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient metal-free cascade oxidative radical addition of styrenes is developed for the construction of 1,3-dichloro-1,5-diarylpentan-5-ones. This protocol presents a practical one-pot procedure that delivers highly functionalized 1,3-dichloro-1,5-diarylpentan-5-ones in moderate-to-good yields with a broad substrate scope under mild conditions.

引用

页码：699 / 702

页数：4

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