Estimating Asymptomatic and Symptomatic Transmission of the COVID-19 First Few Cases in Selenge Province, Mongolia

被引:0
|
作者
Dambadarjaa, Davaalkham [1 ]
Mend, Tsogt [2 ]
Shapiro, Andrew [3 ]
Handcock, Mark S. [3 ]
Mandakh, Undram [4 ]
Enebish, Temuulen [5 ]
Le, Linh-Vi [5 ]
Bandoy, D. J. Darwin R. [5 ,6 ]
Amarjargal, Ambaselmaa [2 ]
Altangerel, Bilegt [2 ]
Chuluunbaatar, Tuvshintur [2 ]
Guruuchin, Uugantsetseg [2 ]
Lkhagvajav, Oyuntulkhuur [2 ]
Enebish, Oyunsuren [7 ]
机构
[1] Mongolian Natl Univ Med Sci, Sch Publ Hlth, Ulaanbaatar, Mongolia
[2] Natl Ctr Communicable Dis, Dept Surveillance & Response, Ulaanbaatar, Mongolia
[3] Univ Calif Los Angeles, Dept Stat, Los Angeles, CA USA
[4] Mongolian Natl Univ Med Sci, Sch Med, Dept Family Med, Ulaanbaatar, Mongolia
[5] World Hlth Org Reg Off Western Pacific, COVID 19 Incident Management Support Team, Manila, Philippines
[6] Univ Philippines Los Banos, Coll Vet Med, Laguna, Philippines
[7] Minist Hlth, Ulaanbaatar, Mongolia
关键词
Bayesian statistics; coronavirus infections/epidemiology*; COVID-19*/epidemiology; family characteristics; field epidemiology; human*; influenza; pandemics*; SARS-CoV-2; FRAMEWORK;
D O I
10.1111/irv.13277
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
BackgroundFollowing the first locally transmitted case in Sukhbaatar soum, Selenge Province, we aimed to investigate the ultimate scale of the epidemic in the scenario of uninterrupted transmission.MethodsThis was a prospective case study following the locally modified WHO FFX cases generic protocol. A rapid response team collected data from November 14 to 29, 2020. We created a stochastic process to draw many transmission chains from this greater distribution to better understand and make inferences regarding the outbreak under investigation.ResultsThe majority of the cases involved household transmissions (35, 52.2%), work transmissions (20, 29.9%), index (5, 7.5%), same apartment transmissions (2, 3.0%), school transmissions (2, 3.0%), and random contacts between individuals transmissions (1, 1.5%). The posterior means of the basic reproduction number of both the asymptomatic cases R0Asy$$ {R}_0<^>{Asy} $$ and the presymptomatic cases R0Pre$$ {R}_0<^>{Pre} $$ (1.35 [95% CrI 0.88-1.86] and 1.29 [95% CrI 0.67-2.10], respectively) were lower than that of the symptomatic cases (2.00 [95% Crl 1.38-2.76]).ConclusionOur study highlights the heterogeneity of COVID-19 transmission across different symptom statuses and underscores the importance of early identification and isolation of symptomatic cases in disease control. Our approach, which combines detailed contact tracing data with advanced statistical methods, can be applied to other infectious diseases, facilitating a more nuanced understanding of disease transmission dynamics.
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页数:9
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