Pre-XDR Congenital Tuberculosis in an Extremely Premature Baby

被引：1
|
作者：
Boast, Alison [1 ,2 ,3 ]
How, Jeu Ann [4 ]
Lau, Charis [4 ,5 ]
Sett, Arun [6 ,7 ,8 ]
Gilby, Damien [4 ]
Burke, Andrew [9 ,10 ]
McWhinney, Brett [11 ]
Wright, Connor [12 ]
Tramontana, Adrian [12 ]
Globan, Maria [13 ]
Denholm, Justin [14 ,15 ]
Graham, Stephen M. [1 ]
Osowicki, Joshua [1 ,2 ,16 ]
机构：
[1] Univ Melbourne, Dept Paediat, Parkville, Vic, Australia
[2] Royal Childrens Hosp Melbourne, Dept Gen Med, Infect Dis Unit, 50 Flemington Rd, Parkville, Vic 3052, Australia
[3] Murdoch Childrens Res Inst, Antimicrobials Res Grp, Parkville, Vic, Australia
[4] Joan Kirner Womens & Childrens Hosp, Newborn Serv, St Albans, Vic, Australia
[5] Joan Kirner Womens & Childrens Hosp, Pharm Dept, St Albans, Vic, Australia
[6] Univ Melbourne, Dept Obstet & Gynaecol, Parkville, Vic, Australia
[7] Royal Womens Hosp, Newborn Res Ctr, Parkville, Vic, Australia
[8] Murdoch Childrens Res Inst, Ctr Res Excellence Newborn Med, Parkville, Vic, Australia
[9] Prince Charles Hosp, Dept Thorac Med, Chermside, Qld, Australia
[10] Univ Queensland, Fac Med, Ctr Clin Res, Brisbane, Australia
[11] Queensland Hlth, Pathol Queensland, Dept Chem Pathol, Herston, Australia
[12] Western Hlth, Dept Infect Dis, St Albans, Vic, Australia
[13] Peter Doherty Inst Infect & Immun, Victorian Infect Dis Reference Lab, Mycobacterium Reference Lab, Parkville, Vic, Australia
[14] Melbourne Hlth, Victorian TB Program, Parkville, Vic, Australia
[15] Univ Melbourne, Peter Doherty Inst Infect & Immun, Dept Infect Dis, Melbourne, Vic, Australia
[16] Murdoch Childrens Res Inst, Trop Dis Res Grp, Parkville, Vic, Australia
来源：
CLINICAL INFECTIOUS DISEASES | 2024年 / 78卷 / 01期
关键词：
congenital tuberculosis; multidrug resistant; premature; neonate; therapeutic drug monitoring;
D O I：
10.1093/cid/ciad540
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
We describe a case of congenital tuberculosis in an extremely premature baby, with rapid molecular detection of a pre-extensively drug-resistant (XDR) pattern of drug resistance. The baby was treated successfully with a regimen including bedaquline and delamanid, drugs not previously described in the treatment of congenital tuberculosis (TB).
引用
收藏
页码：149 / 153
页数：5
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