Anemia and quality of life of chronic kidney disease patients on renal replacement therapy by programmed hemodialysis

Aim. To study relationship between anemia and health-related quality of life (HRQOL) of chronic kidney disease stage 5 patients undergoing renal replacement therapy by programmed hemodialysis.Materials and methods. The study was conducted on the basis of dialysis centers/departments in Moscow. The Russian-language version of the KDQOL-SFTM questionnaire was used to assess the HRQOL of patients. A total of 723 patients were interviewed. Hemoglobin (Hb) levels were assessed in 442 patients. To identify the relationship between Hb level and HRQOL scales, a correlation analysis was performed, as well as a HRQOL analysis in the three groups differing in Hb levels (<100; 100-120 and >120 g/l).Results. Relationship was revealed between Hb and HRQOL of patients on hemodialysis on the scales "symptoms/problems", "pain", "energy/ fatigue" and "summary physical component of health". According to the scales "symptoms/problems" and "energy/fatigue" higher rates were noted among patients with Hb higher than the target level, which confirms the recommendations of a personalized approach to the correction of anemia.Conclusion. HRQOL assessment is important tool for selecting, monitoring and correction of anemia therapy among patients with chronic kidney disease on hemodialysis.