The Effect of Honey, Aloe Vera, and Hydrocolloid Dressing on the Healing Process of Murine Excisional Wounds

被引:0
|
作者
Hernandez-Rodriguez, Jose Enrique [1 ,8 ]
Martin-Barrasa, Jose Luis [2 ,3 ]
Aragon-Sanchez, J. [4 ]
Monzon-Mayor, Maximina [5 ]
Perez-Galvan, Jose Manuel [6 ]
Saavedra-Santana, Pedro [7 ]
Romero-Aleman, Maria del Mar [5 ]
机构
[1] Univ Las Palmas Gran Canaria, Univ Inst Biomed & Hlth Res, Dept Nursing, Las Palmas Gran Canaria, Las Palmas, Spain
[2] Univ Las Palmas Gran Canaria, Dr Negrin Univ Hosp, Res Unit, Las Palmas Gran Canaria, Las Palmas, Spain
[3] Univ Las Palmas Gran Canaria, Univ Inst Anim Hlth, Las Palmas Gran Canaria, Las Palmas, Spain
[4] La Paloma Hosp, Diabetic Foot Unit, Las Palmas Gran Canaria, Las Palmas, Spain
[5] Univ Las Palmas Gran Canaria, Univ Inst Biomed & Hlth Res, Dept Morphol, Las Palmas Gran Canaria, Islas Canarias, Spain
[6] Univ Las Palmas Gran Canaria, SIMACE Facil Res Adv Confocal & Electron Microscop, Las Palmas Gran Canaria, Islas Canarias, Spain
[7] Univ Las Palmas Gran Canaria, Dept Math, Las Palmas Gran Canaria, Islas Canarias, Spain
[8] Las Palmas de Gran Canaria Univ, Inst Biomed & Healthcare Res, Hlth Sci Fac, Nursing Dept, Paseo Blas Cabrera Felipe S-N, Las Palmas Gran Canaria 35016, Canary Islands, Spain
关键词
wound healing; pressure ulcers; honey; aloe; murine model wounds and subcutaneous ring; TOPICAL APPLICATION; GAMMA-IRRADIATION; ANTIBACTERIAL; ANTIBIOFILM; RADIATION; IMPROVES;
D O I
10.1177/15347346231214597
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Chronic ulcers are a major health problem associated with high costs and a loss of quality of life. Because of this, the search for products that accelerate wound healing is a constant, given the need for alternatives that help to alleviate this serious health problem. We analyzed the efficacy of 2 natural products-honey and aloe vera-versus hydrocolloid (HC) dressings as a control group in healing full-thickness wounds. For this purpose, we performed full-thickness excisions of the skin, including the panniculus carnosus, in mice. We inserted a nitrile ring into the subcutaneous cellular tissue simulating the second-intention wound healing course. We found that aloe vera reduced the diameter of the wounds compared to honey (p < .001) and the control group (p < .001).
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页数:9
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