A core-shell structured AuNPs@ZnCo-MOF SERS substrate for sensitive and selective detection of thiram

Surface-enhanced Raman scattering (SERS) enables pesticide residue monitoring to become facile and efficient. In this study, a core-shell structured gold nanoparticles@ZnCo metal-organic framework (AuNPs@ZnCo-MOF) SERS substrate was designed and successfully synthesized for efficient and selective detection of thiram. The bimetallic ZnCo-MOF shell can not only enrich the targeted molecules in the electromagnetic field because of its excellent absorptive capacity, but also act as a stabilized matrix for protecting the AuNPs from aggregation. The AuNPs@ZnCo-MOFs exhibited a high enhancement factor (EF) of 3.51 x 106 and a low detection limit of 1 x 10-7 mol L-1. Besides, the substrate material showed exceptional stability for up to 28 days at room temperature. The AuNPs@ZnCo-MOFs were used to detect thiram which displayed wide linearity (1 x 10-7 to 1 x 10-4 mol L-1) and high recoveries (83.45-99.61%). Moreover, the AuNPs@ZnCo-MOF SERS substrate exhibited excellent anti-interference ability and size selectivity for the target molecules. These indicate that the AuNPs@ZnCo-MOF substrate has great potential for the detection of thiram residues in practical applications. Novel core-shell AuNPs@ZnCo-MOF composites were successfully prepared at room temperature and used as SERS substrates for rapid, sensitive and specific detection of thiram in fruits.