WASTE CURD WATER CATALYSED SYNTHESIS OF BENZIMIDAZOLE DERIVATIVES: A GREEN APPROACH

An effective and novel green approach developed for preparation of 2-substituted benzimidazole. The benzimidazole derivatives prepared by condensation of 2,3-Diamino benzene and substituted benzaldehydes using waste curd water (WCW) under normal reaction condition. The waste curd water has shown its dual action as a solvent and biocatalyst also in the synthesis of Benzimidazole derivatives. This novel synthesis method produced benzimidazole derivatives with short reaction time and good yield of 76-85%. Our protocol is economical, more efficient and environmentally benign than conventional protocols for benzimidazole synthesis.