Recent progress in the application of amidines for the synthesis of N-heterocyclic compounds

被引：0

作者：

Doraghi, Fatemeh ^{[1
]}

Karimian, Somaye ^{[2
]}

Navid, Hamed ^{[3
]}

Ghanbarlou, Mehdi ^{[1
]}

Larijani, Bagher ^{[1
]}

Mahdavi, Mohammad ^{[1
]}

机构：

[1] Univ Tehran Med Sci, Endocrinol & Metab Clin Sci Inst, Endocrinol & Metab Res Ctr, Tehran, Iran

[2] Shiraz Univ Med Sci, Med & Nat Prod Chem Res Ctr, Shiraz, Iran

[3] Univ Tehran, Coll Sci, Sch Chem, Tehran, Iran

来源：

MONATSHEFTE FUR CHEMIE | 2024年 / 155卷 / 05期

关键词：

N-Heterocycle; Synthetic chemistry; Amidine; Nucleophile; Organic transformation; H BOND ACTIVATION; MEDICINAL SIGNIFICANCE; DIVERGENT COUPLINGS; IMIDAMIDES; QUINOLINES; CHEMISTRY; STRATEGY; CONSTRUCTION; QUINAZOLINE; DERIVATIVES;

D O I：

10.1007/s00706-024-03180-w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Nitrogen-containing heterocycles are an inseparable part of many biologically active compounds. Therefore, the synthesis of these structures is of great importance in the field of synthetic chemistry. Due to the presence of two nitrogen atoms in the amidine structure, this molecule can be considered as a dual nucleophile in the synthesis of various heterocycles. The current review highlights recent advances in the application of amidines, in particular, N-arylamidines, as versatile precursors in transition metal-catalyzed, and metal-free reactions for the construction of N-heterocyclic compounds.

引用

页码：419 / 439

页数：21

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