Programming schistosomes - a crisper approach to transgenesis

被引：1
|
作者：
Kalinna, Bernd H. [1 ]
机构：
[1] Charles Sturt Univ, Rural Hlth Res Inst, Schistosomiasis Lab, Orange, NSW, Australia
来源：
TRENDS IN PARASITOLOGY | 2023年 / 39卷 / 11期
关键词：
D O I：
10.1016/j.pt.2023.09.003
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Ittiprasert and colleagues identified genomic safe harbour (GSH) sites in Schistosoma mansoni using computational methods and inserted a transgene into one of the sites through clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9-assisted homology-directed repair. This study outlines a promising strategy for functional genomics to study this parasite that causes a debilitating and neglected tropical disease.
引用
收藏
页码：896 / 897
页数：2
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