Four-Way Wada: SEEG-based mapping with electrical stimulation, high frequency activity, and phase amplitude coupling to complement traditional Wada and functional MRI prior to epilepsy surgery

被引：3

作者：

Bearden, D. J. ^{[1
,2
]}

Ehrenberg, A. ^{[3
]}

Selawski, R. ^{[1
]}

Ono, K. E. ^{[1
,2
]}

Drane, D. L. ^{[2
,5
,6
]}

Pedersen, N. P. ^{[2
]}

Cernokova, I. ^{[7
]}

Marcus, D. J. ^{[1
]}

Luongo-Zink, C. ^{[1
,4
]}

Chern, J. J. ^{[8
]}

Oliver, C. B. ^{[1
]}

Ganote, J. ^{[1
]}

Al-Ramadhani, R. ^{[9
]}

Bhalla, S. ^{[1
]}

Gedela, S. ^{[1
]}

Zhang, G. ^{[1
]}

Kheder, A. ^{[1
,2
,10
]}

机构：

[1] Childrens Healthcare Atlanta, Atlanta, GA USA

[2] Emory Univ, Dept Neurol, Sch Med, Atlanta, GA USA

[3] Nihon Kohden, Irvine, CA USA

[4] William James Coll, Newton, MA USA

[5] Emory Univ, Dept Pediat, Sch Med, Atlanta, GA USA

[6] Univ Washington, Dept Neurol, Sch Med, Seattle, WA USA

[7] Univ North Texas, Denton, TX USA

[8] Childrens Healthcare Atlanta, Dept Neurosurg, Atlanta, GA USA

[9] Univ Pittsburgh, Childrens Hosp, Med Ctr, Pittsburgh, PA 15224 USA

[10] Emory Univ, Pediat Inst, Dept Neurol, Sch Med, Atlanta, GA 30322 USA

来源：

EPILEPSY RESEARCH | 2023年 / 192卷

关键词：

Temporal lobe epilepsy; Epilepsy surgery; Stereoelectroencephalography; Electrical stimulation mapping; High frequency activity; Phase amplitude coupling;

D O I：

10.1016/j.eplepsyres.2023.107129

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Presurgical evaluation of refractory epilepsy involves functional investigations to minimize postoperative deficit. Assessing language and memory is conventionally undertaken using Wada and fMRI, and occasionally supple-mented by data from invasive intracranial electroencephalography, such as electrical stimulation, corticortical evoked potentials, mapping of high frequency activity and phase amplitude coupling. We describe the comparative and complementary role of these methods to inform surgical decision-making and functional prognostication. We used Wada paradigm to standardize testing across all modalities. Postoperative neuropsy-chological testing confirmed deficit predicted based on these methods.

引用

页数：5