Evolving Therapeutic Landscape of Intracerebral Hemorrhage: Emerging Cutting-Edge Advancements in Surgical Robots, Regenerative Medicine, and Neurorehabilitation Techniques

被引：2

作者：

Chen, Danyang ^{[1
]}

Zhao, Zhixian ^{[1
]}

Zhang, Shenglun ^{[2
]}

Chen, Shiling ^{[1
]}

Wu, Xuan ^{[1
]}

Shi, Jian ^{[2
]}

Liu, Na ^{[1
]}

Pan, Chao ^{[1
]}

Tang, Yingxin ^{[1
]}

Meng, Cai ^{[3
]}

Zhao, Xingwei ^{[2
]}

Tao, Bo ^{[2
]}

Liu, Wenjie ^{[4
]}

Chen, Diansheng ^{[5
]}

Ding, Han ^{[2
]}

Zhang, Ping ^{[1
]}

Tang, Zhouping ^{[1
]}

机构：

[1] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Neurol, Wuhan, Hubei, Peoples R China

[2] Huazhong Univ Sci & Technol, Sch Mech Sci & Engn, Wuhan, Hubei, Peoples R China

[3] Beihang Univ, Sch Astronaut, Beijing, Peoples R China

[4] Beijing Wantefu Med Instrument Co Ltd, Beijing, Peoples R China

[5] Beihang Univ, Sch Mech Engn & Automat, Inst Robot, Beijing, Peoples R China

来源：

TRANSLATIONAL STROKE RESEARCH | 2024年

关键词：

Brain-computer interfaces; Intracerebral hemorrhage; Minimally invasive surgery; Neuronal reprogramming; Stem cell transplantation; Surgical robots; MESENCHYMAL STEM-CELLS; INITIAL CONSERVATIVE TREATMENT; MINIMALLY INVASIVE SURGERY; NEURON CONVERSION; STROKE; TRANSPLANTATION; INTERFACE; DEPRESSION; HEMATOMAS; APOPTOSIS;

D O I：

10.1007/s12975-024-01244-x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Intracerebral hemorrhage (ICH) is the most serious form of stroke and has limited available therapeutic options. As knowledge on ICH rapidly develops, cutting-edge techniques in the fields of surgical robots, regenerative medicine, and neurorehabilitation may revolutionize ICH treatment. However, these new advances still must be translated into clinical practice. In this review, we examined several emerging therapeutic strategies and their major challenges in managing ICH, with a particular focus on innovative therapies involving robot-assisted minimally invasive surgery, stem cell transplantation, in situ neuronal reprogramming, and brain-computer interfaces. Despite the limited expansion of the drug armamentarium for ICH over the past few decades, the judicious selection of more efficacious therapeutic modalities and the exploration of multimodal combination therapies represent opportunities to improve patient prognoses after ICH.

引用

页数：15