Versatile applications of transition metal incorporating quinoline Schiff base metal complexes: An overview

被引:33
|
作者
Sonawane, Harshad R. [1 ,3 ]
Vibhute, Baliram T. [2 ]
Aghav, Balasaheb D. [1 ]
Deore, Jaydeep, V [3 ]
Patil, Sanjay K. [1 ]
机构
[1] Univ Mumbai, Dept Chem, Changu Kana Thakur ACS Coll, New Panvel Autonomous, New Panvel 410206, Maharashtra, India
[2] Doshi Vakil Arts & GCUB Sci & Commerce Coll, Dept Chem, Goregaon 402103, Maharashtra, India
[3] GM Vedak Coll Sci, Dept Chem, Tala Raigad 402111, Maharashtra, India
关键词
Schiff base metal complexes; Transition metal ions; Quinoline; Azomethine; Antimicrobial; Antioxidant; Anticancer; DINUCLEAR ZINC(II) COMPLEXES; BIOLOGICAL-ACTIVITIES; DNA-BINDING; CLINICAL PHARMACOKINETICS; COPPER(II) COMPLEXES; MIMICKING ACTIVITY; CRYSTAL-STRUCTURE; CATECHOL OXIDASE; BETA-LACTAMS; FLUORESCENCE;
D O I
10.1016/j.ejmech.2023.115549
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Since the last decade, research on quinoline Schiff base metal complexes has risen substantially due to their versatile applications across many significant fields. Schiff bases are also known as azomethines, aldimines, and imines. Quinoline Schiff base-derived metal complexes are intriguing to study topics. These complexes are employed in biological, analytical, and catalytic fields. Researchers have found that Schiff bases are more bio-logically active when coordinated with metal ions. Research in the biological sciences has shown that hetero-cyclic compounds like quinoline and its derivatives are important. Because of their broad spectrum of activity, quinoline derivatives have been discovered to be effective therapeutic agents for various disorders. Even though various classical synthetic pathways mentioned in the literature are still in use, there is an urgent need for a new, more effective method that is safer for the environment, has a higher yield, generates less hazardous waste, and is easier to use. This highlights the critical need for a safe, eco-friendly approach to quinoline scaffold synthesis. This review focuses exclusively on Schiff base metal complexes derived from quinoline, fabricated and studied in the past ten years, and having anticancer, antibacterial, antifungal, antioxidant, antidiabetic, antiproliferative, DNA-intercalation, and cytotoxic activities.
引用
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页数:26
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