Nanotechnology Involved in Treating Urinary Tract Infections: An Overview

被引:4
|
作者
Crintea, Andreea [1 ]
Carpa, Rahela [2 ]
Mitre, Andrei-Otto [3 ]
Petho, Robert Istvan [4 ]
Chelaru, Vlad-Florin [4 ]
Nadasan, Sebastian-Mihail [4 ]
Neamti, Lidia [1 ]
Dutu, Alina Gabriela [1 ]
机构
[1] Iuliu Hatieganu Univ Med & Pharm, Fac Med, Dept Med Biochem, Cluj Napoca 400349, Romania
[2] Babes Bolyai Univ, Fac Biol & Geol, Dept Mol Biol & Biotechnol, Cluj Napoca 400084, Romania
[3] Iuliu Hatieganu Univ Med & Pharm, Fac Med, Dept Pathophysiol, Cluj Napoca 400349, Romania
[4] Iuliu Hatieganu Univ Med & Pharm, Fac Med, Cluj Napoca 400349, Romania
关键词
urinary tract infections; antimicrobial treatment; nanotechnology; organic nanoparticles; inorganic nanoparticles; mixt nanoparticles; biocompatibility; ZINC-OXIDE NANOPARTICLES; ACYL HOMOSERINE LACTONE; ANTIMICROBIAL RESISTANCE; ESCHERICHIA-COLI; ANTIBACTERIAL ACTIVITY; MOLECULAR-MECHANISMS; DRUG-DELIVERY; ZNO NANOPARTICLES; IMMUNE-RESPONSE; RAPID DETECTION;
D O I
10.3390/nano13030555
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Considered as the most frequent contaminations that do not require hospitalization, urinary tract infections (UTIs) are largely known to cause significant personal burdens on patients. Although UTIs overall are highly preventable health issues, the recourse to antibiotics as drug treatments for these infections is a worryingly spread approach that should be addressed and gradually overcome in a contemporary, modernized healthcare system. With a virtually alarming global rise of antibiotic resistance overall, nanotechnologies may prove to be the much-needed 'lifebuoy' that will eventually suppress this prejudicial phenomenon. This review aims to present the most promising, currently known nano-solutions, with glimpses on clinical and epidemiological aspects of the UTIs, prospective diagnostic instruments, and non-antibiotic treatments, all of these engulfed in a comprehensive overview.
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页数:25
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