A heparan sulfate proteoglycan-mimicking AIE fluorescent probe for SARS-CoV-2 detection

被引：3
|
作者：
Liu, Fang [1 ]
Huang, Yue [1 ]
Li, Yutong [1 ]
Chen, Yongcheng [1 ]
Jin, Qiao [1 ]
Ji, Jian [1 ,2 ]
机构：
[1] Zhejiang Univ, Dept Polymer Sci & Engn, MOE Key Lab Macromol Synth & Functionalizat, Minist Educ, Hangzhou 310027, Peoples R China
[2] Shanxi Zheda Inst Adv Mat & Chem Engn, Taiyuan 030032, Peoples R China
来源：
NEW JOURNAL OF CHEMISTRY | 2024年 / 48卷 / 10期
关键词：
AGGREGATION-INDUCED EMISSION; SERUM;
D O I：
10.1039/d3nj04949c
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A heparan sulfate proteoglycan (HSPG)-mimicking fluorescent probe, tetrasulfonated tetraphenylethene (TPES), with aggregation-induced emission (AIE) characteristics is designed for fast SARS-CoV-2 detection. TPES can adhere to SARS-CoV-2 by the strong interaction between the sulfonic acid groups of TPES and the spike proteins of SARS-CoV-2, leading to a significant fluorescence enhancement. A heparan sulfate proteoglycan (HSPG)-mimicking fluorescent probe, tetrasulfonated tetraphenylethene (TPES), with aggregation-induced emission (AIE) characteristics is developed for fast SARS-CoV-2 detection.
引用
收藏
页码：4208 / 4212
页数：5
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