Retrospective evaluation of real-time estimates of global COVID-19 transmission trends and mortality forecasts

被引:0
|
作者
Bhatia, Sangeeta [1 ,2 ]
Parag, Kris V. [1 ]
Wardle, Jack [1 ]
Nash, Rebecca K. [1 ]
Imai, Natsuko [1 ]
Elsland, Sabine L. Van [1 ]
Lassmann, Britta [3 ]
Brownstein, John S. [4 ]
Desai, Angel [3 ,5 ]
Herringer, Mark [6 ]
Sewalk, Kara [4 ]
Loeb, Sarah Claire [3 ]
Ramatowski, John [3 ]
Cuomo-Dannenburg, Gina [1 ]
Jauneikaite, Elita [1 ]
Unwin, H. Juliette T. [1 ]
Riley, Steven [1 ]
Ferguson, Neil [1 ]
Donnelly, Christl A. [1 ,7 ]
Cori, Anne [1 ]
Nouvellet, Pierre [1 ,8 ]
机构
[1] Imperial Coll London, Sch Publ Hlth, MRC Ctr Global Infect Dis Anal, London, England
[2] UK Hlth Secur Agcy, NIHR Hlth Protect Res Unit Modelling & Hlth Econ, Modelling & Econ Unit, London, England
[3] Int Soc Infect Dis, ProMED Mail, Brookline, MA USA
[4] Boston Childrens Hosp, Computat Epidemiol Lab, Boston, MA USA
[5] Univ Calif Davis, Dept Internal Med, Div Infect Dis, Sacramento, CA USA
[6] Global Healthsites Mapping Project, Healthsites Io, London, England
[7] Univ Oxford, Dept Stat, Oxford, England
[8] Univ Sussex, Sch Life Sci, Brighton, England
来源
PLOS ONE | 2023年 / 18卷 / 10期
基金
英国医学研究理事会; 英国惠康基金;
关键词
EPIDEMIC;
D O I
10.1371/journal.pone.0286199
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Since 8(th) March 2020 up to the time of writing, we have been producing near real-time weekly estimates of SARS-CoV-2 transmissibility and forecasts of deaths due to COVID-19 for all countries with evidence of sustained transmission, shared online. We also developed a novel heuristic to combine weekly estimates of transmissibility to produce forecasts over a 4-week horizon. Here we present a retrospective evaluation of the forecasts produced between 8(th) March to 29(th) November 2020 for 81 countries. We evaluated the robustness of the forecasts produced in real-time using relative error, coverage probability, and comparisons with null models. During the 39-week period covered by this study, both the short- and medium-term forecasts captured well the epidemic trajectory across different waves of COVID-19 infections with small relative errors over the forecast horizon. The model was well calibrated with 56.3% and 45.6% of the observations lying in the 50% Credible Interval in 1-week and 4-week ahead forecasts respectively. The retrospective evaluation of our models shows that simple transmission models calibrated using routine disease surveillance data can reliably capture the epidemic trajectory in multiple countries. The medium-term forecasts can be used in conjunction with the short-term forecasts of COVID-19 mortality as a useful planning tool as countries continue to relax public health measures.
引用
收藏
页数:17
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