A covalent organic framework-based nanoreactor for enhanced photothermal therapy via inhibiting intracellular heat defense systems

被引：5
|
作者：
Li, Yan-An [1 ]
Wan, Jing-Jing [1 ]
Li, Wen-Yan [1 ]
Guan, Qun [1 ]
Dong, Yu-Bin [1 ]
机构：
[1] Shandong Normal Univ, Collaborat Innovat Ctr Functionalized Probes Chem, Coll Chem Chem Engn & Mat Sci, Key Lab Mol & Nano Probes,Minist Educ, Jinan 250014, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 48期
关键词：
INDOCYANINE GREEN; HYDROGEN-PEROXIDE; NANOPARTICLES; FLUORESCENCE; CANCER;
D O I：
10.1039/d3cc01153d
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we report an indocyanine green (ICG)-decorated and glucose oxidase (GOx)-loaded nanoscale composite COF material via a stepwise post-synthetic modification. The obtained GOx@COF-ICG can achieve synergistic inhibition of intracellular heat defense systems through starvation therapy to enhance photothermal therapy of tumors.
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页码：7463 / 7466
页数：4
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