Immune Responses and Breakthrough Infections After COVID-19 Vaccination

被引：2
|
作者：
Kwon, Ki Tae [1 ,2 ]
机构：
[1] Kyungpook Natl Univ, Chilgok Hosp, Sch Med, Dept Internal Med,Div Infect Dis, Daegu, South Korea
[2] Kyungpook Natl Univ, Dept Internal Med, Div Infect Dis, Chilgok Hosp, 807 Hoguk Ro, Daegu 41404, South Korea
来源：
JOURNAL OF KOREAN MEDICAL SCIENCE | 2023年 / 38卷 / 20期
关键词：
D O I：
10.3346/jkms.2023.38.e185
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Coronavirus diseases 2019 (COVID-19) vaccines have demonstrated high efficacy and effectiveness in preventing SARS-CoV-2 infection and reducing the risk of emergency room visits, hospitalizations, intensive care unit admissions, and deaths due to symptomatic COVID-19, especially severe and critical COVID-19.1 However, concerns have been raised about the occurrence of breakthrough infections mainly due to the waning of protection over time after vaccination and the appearance of viral variants. To address the waning immunity after vaccination, booster dose of COVID-19 vaccines was introduced. A BNT162b2 booster after either the ChAdOx1 or BNT162b2 primary series substantially increased protection, but that protection waned over time as well.2 Differences in immune response and effectiveness between ChAdOx1 and BNT162b2 based vaccination programs have not yet been consistently observed. © 2023 The Korean Academy of Medical Sciences.
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Breakthrough infections after COVID-19 vaccination: Insights, perspectives and challenges
    Amanatidou, Evropi
    Gkiouliava, Anna
    Pella, Eva
    Serafidi, Maria
    Tsilingiris, Dimitrios
    Vallianou, Natalia G.
    Karampela, I. rene
    Dalamaga, Maria
    [J]. METABOLISM OPEN, 2022, 14
  • [2] COVID-19 breakthrough infections in rheumatic diseases patients after vaccination
    Alshukairi, Abeer N.
    Al-Omari, Awad
    Albeity, Abdurahman
    Alandijany, Thamir A.
    Hassan, Ahmed M.
    El-Kafrawy, Sherif A.
    Dada, Ashraf
    Al Hroub, Mohammad K.
    El-Saed, Aiman
    Bissar, Lina S.
    Daghmush, Radwan M.
    Al-Ghamdi, Saeed M. G.
    Perlman, Stanley
    Azhar, Esam I.
    Halabi, Hussein
    [J]. JOURNAL OF INFECTION AND PUBLIC HEALTH, 2022, 15 (06) : 685 - 688
  • [3] Salivary immune responses after COVID-19 vaccination
    Nguyen, Kenny
    Relja, Boris
    Epperson, Monica
    Park, So Hee
    Thornburg, Natalie J.
    Costantini, Veronica P.
    Vinje, Jan
    [J]. PLOS ONE, 2024, 19 (09):
  • [4] COVID-19 vaccination and breakthrough infections in patients with cancer
    Schmidt, A. L.
    Labaki, C.
    Hsu, C-Y
    Bakouny, Z.
    Balanchivadze, N.
    Berg, S. A.
    Blau, S.
    Daher, A.
    El Zarif, T.
    Friese, C. R.
    Griffiths, E. A.
    Hawley, J. E.
    Hayes-Lattin, B.
    Karivedu, V
    Latif, T.
    Mavromatis, B. H.
    McKay, R. R.
    Nagaraj, G.
    Nguyen, R. H.
    Panagiotou, O. A.
    Portuguese, A. J.
    Puc, M.
    Dutra, M. Santos
    Schroeder, B. A.
    Thakkar, A.
    Wulff-Burchfield, E. M.
    Mishra, S.
    Farmakiotis, D.
    Shyr, Yu
    Warner, J. L.
    Choueiri, T. K.
    [J]. ANNALS OF ONCOLOGY, 2022, 33 (03) : 340 - 346
  • [5] Immune Response in Moderate to Critical Breakthrough COVID-19 Infection After mRNA Vaccination
    Paniskaki, Krystallenia
    Anft, Moritz
    Meister, Toni L.
    Marheinecke, Corinna
    Pfaender, Stephanie
    Skrzypczyk, Sarah
    Seibert, Felix S.
    Thieme, Constantin J.
    Konik, Margarethe J.
    Dolff, Sebastian
    Anastasiou, Olympia
    Holzer, Bodo
    Dittmer, Ulf
    Queren, Christine
    Fricke, Lutz
    Rohn, Hana
    Westhoff, Timm H.
    Witzke, Oliver
    Stervbo, Ulrik
    Roch, Toralf
    Babel, Nina
    [J]. FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [6] Incidence of breakthrough infections after COVID-19 vaccination among the COVID-19 vaccine recipients at a Tertiary Care Hospital in Srinagar
    Fazili, Anjum
    Ain, Syed Najmul
    Shah, Rohul Jabeen
    Raja, Ferheen Nazir
    Farhat, Deeba
    Nazir, Isra
    [J]. INDIAN JOURNAL OF PUBLIC HEALTH, 2023, 67 (02) : 305 - 308
  • [7] Association of COVID-19 Vaccination With Breakthrough Infections and Complications in Patients With Cancer
    Gong, Inna Y.
    Vijenthira, Abi
    Powis, Melanie
    Calzavara, Andrew
    Patrikar, Aditi
    Sutradhar, Rinku
    Hicks, Lisa K.
    Wilton, Drew
    Singh, Simron
    Krzyzanowska, Monika K.
    Cheung, Matthew C.
    [J]. JAMA ONCOLOGY, 2023, 9 (03) : 386 - 394
  • [8] Analysis of immune responses in patients with CLL after heterologous COVID-19 vaccination
    Lee, Hye Kyung
    Hoechstetter, Manuela A.
    Buchner, Maike
    Pham, Trang Thu
    Huh, Jin Won
    Mueller, Katharina
    Zange, Sabine
    von Buttlar, Heiner
    Girl, Philipp
    Woelfel, Roman
    Brandmeier, Lisa
    Pfeuffer, Lisa
    Furth, Priscilla A.
    Wendtner, Clemens -Martin
    Hennighausen, Lothar
    [J]. BLOOD ADVANCES, 2023, 7 (10) : 2214 - 2227
  • [9] COVID-19 vaccine breakthrough infections
    Gupta, Ravindra K.
    Topol, Eric J.
    [J]. SCIENCE, 2021, 374 (6575) : 1561 - 1562
  • [10] Breakthrough COVID-19 Infections After mRNA Vaccination in Solid Organ Transplant Recipients in Miami, Florida
    Anjan, Shweta
    Natori, Yoichiro
    Fernandez Betances, Anmary A.
    Agritelley, Matthew S.
    Mattiazzi, Adela
    Arosemena, Leopoldo
    Andrews, David M.
    Simkins, Jacques
    Guerra, Giselle
    Abbo, Lilian M.
    [J]. TRANSPLANTATION, 2021, 105 (10) : E139 - E141
12345