Synthesis, Spectroscopic, and Thermal Analyses of 2-Oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate

被引:1
|
作者
Becerra, Diana [1 ]
Rojas, Hugo [1 ]
Castillo, Juan-Carlos [1 ]
机构
[1] Univ Pedag & Tecnol Colombia, Escuela Ciencias Quim, Ave Cent Norte 39-115, Tunja 150003, Colombia
关键词
8-hydroxyquinolin-2(1H)-one; O-acylation reaction; 2-oxoquinoline derivatives; TAUTOMERISM; QUINOLIN-2(1H)-ONES; DESIGN;
D O I
10.3390/M1672
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The 2-oxo-1,2-dihydroquinolin-8-yl 4-chlorobenzoate was synthesized in good yield using a triethylamine-mediated O-acylation reaction between 8-hydroxyquinolin-2(1H)-one and 4-chlorobenzoyl chloride in acetonitrile at room temperature. This methodology is notable for its clean reaction profile and straightforward procedure. The 2-oxoquinoline derivative was characterized using spectroscopic, spectrometric, and thermal analyses, enabling a comprehensive understanding of its molecular structure and thermal properties.
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页数:7
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