?-Glutamyltranspeptidase and pH based "AND" logic gate fluorescent probe for orthotopic breast tumor imaging

被引：14
|
作者：
Zhang, Li-Na [1 ]
Zhang, Hong [1 ]
Chen, Shan-Yong [1 ]
Liu, Yan-Zhao [1 ]
Yang, Xiao-Hua [1 ]
Xiang, Fei-Fan [1 ]
Liu, Yan-Hong [1 ]
Li, Kun [1 ]
Yu, Xiao-Qi [1 ,2 ]
机构：
[1] Sichuan Univ, Coll Chem, Key Lab Green Chem & Technol, Minist Educ, Chengdu 610064, Peoples R China
[2] Xihua Univ, Dept Chem, Asymmetr Synth & Chiral Technol Key Lab Sichuan Pr, Chengdu 610039, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 19期
基金：
中国国家自然科学基金;
关键词：
Computer circuits - Fluorescence - Medical imaging - Probes - Silicon - Surgery - Tumors;
D O I：
10.1039/d2cc06568a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An "AND " logic gate-based NIR fluorescent probe Si-NH2-Glu was developed based on novel meso-amine Si-Rhodamine, which combined gamma-glutamyl transpeptidase and pH dual-responsive sites. The features of Si-NH2-Glu enable it to be applied in orthotopic tumor imaging and fluorescence-guided surgery.
引用
收藏
页码：2795 / 2798
页数：4
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