ALSUntangled #73: Lion's Mane

被引：0

作者：

Muhana, Maya ^{[1
]}

Lund, Issac ^{[1
]}

Bromberg, Mark ^{[2
]}

Wicks, Paul ^{[3
]}

Benatar, Michael ^{[4
]}

Barnes, Benjamin ^{[1
]}

Pierce, Kaitlyn ^{[5
]}

Ratner, Dylan ^{[6
]}

Brown, Andrew ^{[4
]}

Bertorini, Tulio ^{[7
]}

Barkhaus, Paul ^{[8
]}

Carter, Greg ^{[9
]}

Cadavid, Javier Mascias ^{[10
]}

McDermott, Christopher ^{[11
]}

Glass, Jonathan D. ^{[12
]}

Pattee, Gary ^{[13
]}

Armon, Carmel ^{[14
]}

Bedlack, Richard ^{[15
]}

Li, Xiaoyan ^{[15
]}

机构：

[1] Augusta Univ, Med Coll Georgia, Augusta, GA USA

[2] Univ Utah, Dept Neurol, Salt Lake City, UT USA

[3] Wicks Digital Hlth, Lichfield, England

[4] Univ Miami, Dept Neurol, Miami, FL USA

[5] Univ N Carolina, Neurosci Ctr, Chapel Hill, NC USA

[6] Tulane Univ, New Orleans, LA USA

[7] Univ Tennessee Hlth Sci Ctr, Dept Neurol, Memphis, TN USA

[8] Med Coll Wisconsin, Dept Neurol, Milwaukee, WI USA

[9] Washington State Univ, Elson S Floyd Coll Med, Dept Rehabil, Spokane, WA USA

[10] Hosp Carlos III La Paz, Neurol Dept, Madrid, Spain

[11] Univ Sheffield, Sheffield Inst Translat Neurosci, Sheffield, England

[12] Emory Univ, Dept Neurol, Atlanta, GA USA

[13] Univ Nebraska Med Ctr, Dept Neurol, Omaha, NE USA

[14] Shamir Med Ctr, Dept Neurol, Zerifin, Israel

[15] Duke Univ, Dept Neurol, 932 Morreene Rd, Durham, NC 27705 USA

来源：

AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION | 2024年 / 25卷 / 3-4期

关键词：

ALS; Lion's Mane; Hericium erinaceus; HERICIUM-ERINACEUS; MEDICINAL MUSHROOM; ANTIOXIDANT; MYCELIA; BRAIN;

D O I：

10.1080/21678421.2023.2296557

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Lion's Mane (Hericium erinaceus) has historically been used as traditional medicine in Asia and Europe for its potential benefits in fighting infection and cancer. It has gained interest in the neurodegenerative disease field because of its mechanisms of action; these include anti-inflammation, neuroprotection, and promoting neurite growth demonstrated in various cell and animal models. A very small, double-blind, placebo-controlled trial in patients with mild cognitive impairment showed a temporary improvement in cognitive function; this finding has yet to be replicated. However, there have been no studies in ALS cell or animal models or in humans with ALS. Lion's Mane appears safe and inexpensive when consumed in powder or capsule, but one anaphylactic case was reported after a patient consumed fresh Lion's Mane mushroom. Currently, we do not have enough information to support the use of Lion's Mane for treating ALS. We support further research in ALS disease models and clinical trials to study its efficacy.

引用

页码：420 / 423

页数：4

共 50 条

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