Postnatal corticosteroid treatment as a risk factor for false positivity in severe combined immunodeficiency newborn screening

被引：0

作者：

Chen, Po-Sung ^{[2
,3
]}

Lee, Ju ^{[3
,4
]}

Pan, Hui-Ping ^{[5
]}

Lin, Yuh-Jyh ^{[3
]}

Lin, Yung-Chieh ^{[3
]}

Chang, Yu-Shan ^{[3
]}

Chen, Yen-Ju ^{[3
]}

Yen, Chia-Liang ^{[1
]}

Lin, Ching-Wei ^{[3
]}

Chen, Chih-An ^{[3
,6
]}

Shieh, Chi-Chang ^{[1
,3
]}

机构：

[1] Natl Cheng Kung Univ Tainan, Inst Clin Med, Coll Med, Tainan, Taiwan

[2] Sin Lau Christian Hosp, Dept Pediat, Tainan, Taiwan

[3] Natl Cheng Kung Univ Hosp, Dept Pediat, Tainan, Taiwan

[4] Kuo Gen Hosp, Dept Pediat, Tainan, Taiwan

[5] Natl Cheng Kung Univ Hosp, Genet Ctr, Tainan, Taiwan

[6] Natl Cheng Kung Univ, Inst Clin Med, Coll Med, 138 Sheng Li Rd, Tainan 704, Taiwan

来源：

JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | 2023年 / 56卷 / 04期

关键词：

Corticosteroid; Severe combined immunodeficiency; SCID; False positive; Newborn screening;

D O I：

10.1016/j.jmii.2023.02.001

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

From 2011, 37 children were referred to a hospital due to low levels of T cell receptor excision circles (TRECs) from newborn screening. Among them, three children were immunologically characterized and followed up to show that postnatal corticosteroid usage may be among the causes of false positivity in TRECs screening.Copyright (c) 2023, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by

引用

页码：871 / 874

页数：4

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