Fahr's syndrome with hypoparathyroidism, thrombocytopenia, and seizure: a rare case report

被引:0
|
作者
Katwal, Shailendra [1 ,5 ]
Bhandari, Sushmita [2 ]
Ghimire, Aastha [3 ]
Ghimire, Prasoon [4 ]
机构
[1] Dadeldhura Subreg Hosp, Dept Radiol, Dadeldhura, Nepal
[2] Shankar Nagar Hlth Post, Butwol, Nepal
[3] Patan Acad Hlth Sci, Kathmandu, Nepal
[4] Dhaulagiri Hosp, Dept Radiol, Baglung, Nepal
[5] Dadeldhura Subreg Hosp, Dept Radiol, Dadeldhura, Tufandada, Nepal
来源
ANNALS OF MEDICINE AND SURGERY | 2023年 / 85卷 / 08期
关键词
case report; Fahr's syndrome; thrombocytopenia; hypoparathyroidism; hypocalcemia; CALCIFICATION;
D O I
10.1097/MS9.0000000000001032
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Introduction and Importance:Fahr's syndrome, also known as bilateral striatopallidodentate calcinosis is a rare neurological disorder that is characterized by abnormal deposition of calcium in the basal ganglia, cerebellar dentate nuclei, and cerebral cortical white matter. The authors report an extremely uncommon case of Fahr's syndrome with thrombocytopenia, hypoparathyroidism, and seizure. Case Presentation:A 32-year-old male was brought with a repeated history of twitching of hands, tingling sensation, and uncontrolled seizure despite medications. Clinical Discussion:Computed tomography findings showed bilateral basal ganglia, cerebellar dentate nuclei, and subcortical cerebral white matter calcifications. Laboratory studies revealed reduced levels of calcium, parathyroid hormone, and thrombocyte count. Based on these investigations Fahr's syndrome probably due to hypoparathyroidism with thrombocytopenia was diagnosed. The patient was initially treated with intravenous calcium gluconate and platelet transfusion followed by oral calcium supplementation. Conclusion:Fahr's syndrome due to hypoparathyroidism should be suspected in any patient with neurological symptoms and hypocalcemia. Seizures in the patient of Fahr's syndrome with thrombocytopenia could be very detrimental due to the risk of intracranial hemorrhage. Hence, treatment should be started as early as possible.
引用
收藏
页码:4131 / 4133
页数:3
相关论文
共 50 条
  • [1] Hypoparathyroidism, Hypothyroidism and Thrombocytopenia: Rare Constellation of Fahr's Syndrome
    Malik, Nilma
    Pattan, Vishwanath
    Nai, Qiang
    Yousif, Abdalla
    [J]. JOURNAL OF ENDOCRINOLOGY AND METABOLISM, 2014, 4 (04) : 110 - 111
  • [2] HYPOPARATHYROIDISM WITH FAHR'S SYNDROME: A CASE REPORT
    Rosero, O. O.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2020, 31 (SUPPL 1) : S186 - S186
  • [3] A Case of Seizure Revealing Fahr's Syndrome with Primary Hypoparathyroidism
    Lee, Yoo Jin
    Park, Sihyung
    Kim, Yang Wook
    Park, Kang Min
    Kim, Il Hwan
    Park, An Han
    Park, Bong Soo
    [J]. AMERICAN JOURNAL OF CASE REPORTS, 2018, 19 : 1430 - 1433
  • [4] Fahr's syndrome and idiopathic hypoparathyroidism - A case report
    Marinkovic, Dejan M.
    Dragovic, Tamara
    Kikovic, Sasa
    Jankovic, Snezana Kuzmic
    Djuran, Zorana
    Hajdukovic, Zoran
    [J]. VOJNOSANITETSKI PREGLED, 2017, 74 (02) : 184 - 188
  • [5] Fahr's syndrome associated with hypoparathyroidism: A case report
    Sarna, Mukesh Kumar
    Goel, Pallaavi
    Bhargava, Varun
    Parakh, Rishabh
    [J]. JOURNAL OF THE ROYAL COLLEGE OF PHYSICIANS OF EDINBURGH, 2023, 53 (04): : 283 - 287
  • [6] Hypoparathyroidism with Fahr's syndrome: A case report and review of the literature
    Zhou, Yuan-Yuan
    Yang, Ying
    Qiu, Hong-Mei
    [J]. WORLD JOURNAL OF CLINICAL CASES, 2019, 7 (21) : 3662 - 3670
  • [7] Hypoparathyroidism with Fahr's syndrome: A case report and review of the literature
    Yuan-Yuan Zhou
    Ying Yang
    Hong-Mei Qiu
    [J]. World Journal of Clinical Cases, 2019, 7 (21) : 3662 - 3670
  • [8] A Rare Case Report Of Fahr's Syndrome
    Nigam, Sandeep
    [J]. INDIAN JOURNAL OF PSYCHIATRY, 2018, 60 (05) : 158 - 158
  • [9] Hypoparathyroidism and Fahr's syndrome: case series
    de Arruda, Anna Catarina Gatzk
    Guerra, Amanda Carolina Damasceno Zanuto
    Pessoa, Carlos Henrique
    Marquezine, Guilherme Figueiredo
    Delfino, Vinicius Daher Alvares
    [J]. JORNAL BRASILEIRO DE NEFROLOGIA, 2022, 44 (04): : 592 - 596
  • [10] Hypoparathyroidism and Fahr's Syndrome: A Case Series
    Berrabeh, Soumiya
    Messaoudi, Najoua
    Elmehraoui, Ouafae
    Assarrar, Imane
    Karabila, Ikram
    Jamal, Anouar
    Zeryouh, Nabila
    Rouf, Siham
    Latrech, Hanane
    [J]. CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (06)