The German Transplantation Registry Reveals Deficiencies in the Listing Process for Kidney Transplantation

被引:1
|
作者
von Samson-Himmelstjerna, Friedrich A. [1 ]
Kolbrink, Benedikt [1 ]
Kakavand, Nassim [1 ]
Zacharias, Helena U. [2 ,3 ]
Schulte, Kevin [1 ]
机构
[1] Univ Hosp Schleswig Holstein, Dept Nephrol & Hypertens, Kiel, Germany
[2] Peter L Reichertz Inst Med Informat TU Braunschwei, Hannover Med Sch, Hannover, Germany
[3] Hannover Med Sch, Hannover, Germany
来源
KIDNEY INTERNATIONAL REPORTS | 2023年 / 8卷 / 12期
关键词
allocation; kidney transplantation; listing time; waiting list; Eurotransplant; German transplantation registry; TIME;
D O I
10.1016/j.ekir.2023.09.031
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction: The time from dialysis onset to enrollment on the kidney waiting list (listing time) is a crucial step on the path to receiving a kidney allograft; however, this process has received very little research attention in the Eurotransplant (ET) area.Methods: We retrospectively analyzed data from the German transplantation registry, including patients who were on the waiting list for a first kidney transplant in Germany between 2006 and 2016. Listing time was evaluated using a mixed linear model. The outcomes on the kidney waiting list were assessed using competing risk analyses.Results: We assessed a total of 43,955 patients. Listing occurred at a higher pace in patients receiving living donor transplantations (median 0.4 years from dialysis onset) than in deceased donor trans-plantations (Eurotransplant Kidney Allocation System [ETKAS] 1.1 years, European Senior Program [ESP] 1.4 years, Acceptable Mismatch program 1.3 years), with 28.5% of living donor transplantations performed preemptively. There was only modest variation in listing time between the transplant centers. Patients with a history of viral infection, high immunization; hemodialysis patients; and patients with a higher body mass index (BMI) had a delayed listing process. Two of 3 patients listed in the ETKAS, excluding those with potential bonus points (pediatric, other organ transplantations), were eventually transplanted. Older pa-tients, male patients, patients with blood type O, and patients with diabetic nephropathy as the underlying renal disease had the highest risk not to proceed to transplantation.Conclusion: Although long waiting times remain the biggest hurdle for transplantation in Germany, there is ample room for improvement of the listing process.
引用
收藏
页码:2701 / 2708
页数:8
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