Alginate Core-Shell Capsules Production through Coextrusion Methods: Principles and Technologies

被引:6
|
作者
Bennacef, Chanez [1 ,2 ]
Desobry-Banon, Sylvie [1 ]
Probst, Laurent [2 ]
Desobry, Stephane [1 ]
机构
[1] Univ Lorraine, Lab Ingn Biomol LIBio, ENSAIA, 2 Ave Foret Haye, F-54505 Vandoeuvre Les Nancy, France
[2] Cookal SAS Co, 19 Ave Meurthe, F-54320 Nancy, France
关键词
coextrusion; alginate; encapsulation; marine polymer; hydrogel; dripping; jetting; centrifugal coextrusion; EHD; MICROCAPSULES; MICROENCAPSULATION; EXTRUSION; ENCAPSULATION; FABRICATION; TRANSITION; DESIGN;
D O I
10.3390/md21040235
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
This paper provides an overview of coextrusion methods for encapsulation. Encapsulation involves the coating or entrapment of a core material such as food ingredients, enzymes, cells, or bioactives. Encapsulation can help compounds add to other matrices, stabilize compounds during storage, or enable controlled delivery. This review explores the principal l coextrusion methods available that can be used to produce core-shell capsules through the use of coaxial nozzles. Four methods for encapsulation by coextrusion are examined in detail, including dripping, jet cutting, centrifugal, and electrohydrodynamic systems. The targeted capsule size determines the appropriate parameters for each method. Coextrusion technology is a promising encapsulation technique able to generate core-shell capsules in a controlled manner, which can be applied to cosmetic, food, pharmaceutical, agriculture, and textile industries. Coextrusion is an excellent way to preserve active molecules and present a significant economic interest.
引用
收藏
页数:16
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