Visible-Light Photoredox-Catalyzed Divergent 1,2-Diacylation and Hydroacylation of Alkenes with Carboxylic Acid Anhydride

被引：11
|
作者：
Zhou, Youkang [1 ]
Zhao, Lirong [1 ]
Hu, Mingyou [1 ]
Duan, Xin-Hua [1 ]
Liu, Le [1 ]
机构：
[1] Xi An Jiao Tong Univ, Sch Chem, Xian 710049, Peoples R China
来源：
ORGANIC LETTERS | 2023年 / 25卷 / 28期
基金：
中国国家自然科学基金;
关键词：
METAL; 1,4-DIKETONES; POTENTIALS; REDUCTION; ACYLATION; RADICALS; STYRENES; ACCESS;
D O I：
10.1021/acs.orglett.3c01787
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A photoredox-catalyzeddivergent 1,2-dicarbonylation and hydroacylationof alkenes with acid anhydride is presented. This approach offersa mild and efficient entry to 1,4-dicarbonyl compounds bearing all-carbonquaternary centers, exhibiting a broad substrate scope and high functionalgroup compatibility. Hydrocarbonylaltion of alkenes can also be realizedby simply introducing a proton source to the reaction system. Mechanisminvestigations support a radical addition/radical-polar crossovercascade.
引用
收藏
页码：5268 / 5272
页数：5
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