Novel synthesis of nano-amino acid-based ionic liquid and its application for preparing DHPMs and xanthenes under solvent-free conditions

In this study, glycine-based ionic liquid ([Gly-H][OTs]) was synthesized through a reaction of glycine with rho-toluenesulfonic acid in water. The synthesized IL was utilized for the one-pot, multi-component synthesis of 3,4-dihydropyrimidin-2(1H)ones, 14-aryl-14H-dibenzo[a,j]xanthenes and 12-aryl-8,9,10,12-tetrahydrobenzo [a] xanthene-11-ones under solvent-free condition. The prepared IL indicates desirable catalytic activity in organic reactions under solvent-free conditions with the high reusability of four runs. The proposed protocol's main advantages are the originality of prepared [Gly-H][OTs], organic green synthesis under solvent-free conditions, high product yields, and less reaction times.