Humanized PD-1 knock-in mice as a model system for combination therapies with human specific PD-1 therapeutics

被引:0
|
作者
Metzger, Philipp
Sonega, Fabiane
Berthomme, Herve
Obodozie, Cynthia
Weber, Holger
机构
关键词
D O I
10.1158/1538-7445.AM2023-5194
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
5194
引用
收藏
页数:2
相关论文
共 50 条
  • [1] Validation of humanized PD-1 knock-in mice as an emerging model to evaluate human specific PD-1 therapeutics
    Avrutskaya, Anya
    Sonego, Fabiane
    Hauser, Jacob
    O'Koren, Emily
    Martin, Gaelle
    Chaix, Julie
    Ball, Robin
    Bui, Thi
    Belle, Ian
    Hall, Chassidy
    Thiam, Kader
    De Marval, Paula L. Miliani
    CANCER RESEARCH, 2019, 79 (13)
  • [2] In vivo characterization of anti-PD-1 antibody REGN2810 in human PD-1 knock-in mice
    Burova, Elena
    Allbritton, Omaira
    Poueymirou, William
    Lai, Venus
    Waite, Janelle
    Skokos, Dimitris
    Papadopoulos, Nicholas
    Murphy, Drew
    Lowy, Israel
    Ioffe, Ella
    Thurston, Gavin
    CANCER IMMUNOLOGY RESEARCH, 2016, 4 (01)
  • [3] Humanized PD-1 Knock-in Mice Reveal Nivolumab's Inhibitory Effects on Glioblastoma Tumor Progression In Vivo
    Chiang, Chun-Yu
    Huang, Meng-Chu
    Tsai, Shih-Chong
    Hsu, Fei-Ting
    Liao, Tsai-Lan
    Yu, Jei-Hwa
    Lin, Tzu-Hsiang
    Huang, Hua-Hsih
    Liao, Pen-An
    IN VIVO, 2023, 37 (05): : 1991 - 2000
  • [4] Characterization of the Anti-PD-1 Antibody REGN2810 and Its Antitumor Activity in Human PD-1 Knock-In Mice
    Burova, Elena
    Hermann, Aynur
    Waite, Janelle
    Potocky, Terra
    Lai, Venus
    Hong, Seongwon
    Liu, Matt
    Allbritton, Omaira
    Woodruff, Amy
    Wu, Qi
    D'Orvilliers, Amanda
    Garnova, Elena
    Rafique, Ashique
    Poueymirou, William
    Martin, Joel
    Huang, Tammy
    Skokos, Dimitris
    Kantrowitz, Joel
    Popke, Jon
    Mohrs, Markus
    MacDonald, Douglas
    Ioffe, Ella
    Olson, William
    Lowy, Israel
    Murphy, Andrew
    Thurston, Gavin
    MOLECULAR CANCER THERAPEUTICS, 2017, 16 (05) : 861 - 870
  • [5] Clinical PD-1/PD-L1 Blockades in Combination Therapies for Lymphomas
    Katsuya, Hiroo
    Suzumiya, Junji
    Kimura, Shinya
    CANCERS, 2023, 15 (22)
  • [6] Generation of humanized PD-1/PD-L1/CD94/NKG2A mice for evaluating novel combination therapies
    He, Fang
    Yuan, Jiangfeng
    Shan, Yawen
    Bahetiyaer, Huwatibieke
    Xu, Qingqing
    Frame, Jenna
    Lin, Qingcong
    Zhou, Xiaofei
    Shang, Chengzhang
    CANCER RESEARCH, 2024, 84 (06)
  • [7] Humanized PD-1/LAG-3 mice for preclinical evaluation of combination therapy
    Duan, Feifei
    Yang, Xiaoliu
    Ju, Cunxiang
    Zhao, Jing
    Gao, Xiang
    Chen, Santi Suryani
    CANCER RESEARCH, 2022, 82 (12)
  • [8] Augmented Antitumor Effect of Unripe Rubus coreanus Miquel Combined with Oxaliplatin in a Humanized PD-1/PD-L1 Knock-In Colorectal Cancer Mouse Model
    Lee, Eun-Ji
    Yang, Ju-Hye
    Choi, Jang-Gi
    Chung, Hwan-Suck
    CELLS, 2022, 11 (18)
  • [9] Antitumor Effect of Korean Red Ginseng through Blockade of PD-1/PD-L1 Interaction in a Humanized PD-L1 Knock-In MC38 Cancer Mouse Model
    Lee, Eun-Ji
    Yang, Ju-Hye
    Yang, Hye Jin
    Cho, Chong-Kwan
    Choi, Jang-Gi
    Chung, Hwan-Suck
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (03)
  • [10] Combination Strategies PD-1/PD-L1 Antagonists
    Sznol, Mario
    CANCER JOURNAL, 2018, 24 (01): : 54 - 57