Synthesis of 6,7-dihydro-5H-benzo[c]-1,2,4-triazolo[3,4-a]azepines and 6,7-dihydro-5H-benzo[c]tetrazolo[5,1-a]azepines

被引：0
|
作者：
Glushkov, Vladimir A. [1 ,2 ]
Mosheva, Kseniya A. [1 ,2 ]
Zaitsev, Mark M. [2 ]
Pelykh, Vera S. [2 ]
Karasik, Valeriya I. [2 ]
Andreev, Alexander I. [2 ]
Dmitriev, Maksim V. [2 ]
机构：
[1] Ural Branch Russian Acad Sci, Inst Tech Chem, 3 Akademika Koroleva St, Perm 614068, Russia
[2] Perm State Univ, 15 Bukireva St, Perm 614990, Russia
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2023年 / 58卷 / 12期
关键词：
benzo[c]azepines; hetarylhydrazines; tetrazolo[5,1-a]azepines; 1,2,4-triazolobenzo[3,4-a]azepines;
D O I：
10.1007/s10593-023-03149-3
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Cyclization of 1-hydrazinyl-3,3-dimethyl-3,4-tetrahydro-5H-benzo[c]azepine with ethyl orthoformate gave 5,5-dimethyl-6,7-dihydro-5H- benzo[c]-1,2,4-triazolo[3,4-a]azepine, and its reaction with acetic acid afforded 3,5,5-trimethyl-9,10-dimethoxy-6,7-dihydro-5?-benzo[c]-1,2,4-triazolo[3,4-a]azepine. Nitrosation of 1-hydrazino-3,3-dimethyl-3,4-tetrahydro-5H-benzo[c]azepine led to the formation of substituted 6,7-dihydro-5H-benzo[c]tetrazolo[5,1-a]azepines.
引用
收藏
页码：727 / 731
页数：5
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