Tetrahydronaphthaline Sulphonamide-Based Deriva- tives Selectively Target Anti-apoptotic BCL2 Protein: Drug Likeness and in silico ADMET Studies

被引：0
|
作者：
Mounier, Marwa M. [1 ]
Mohamed, Hanaa S. [2 ]
Elrashedy, Ahmed A. [3 ]
机构：
[1] Natl Res Ctr, Pharmaceut & Drug Ind Res Inst, Dept Pharmacognosy, Cairo 12622, Egypt
[2] Natl Res Ctr, Pharmaceut & Drug Ind Res Inst, Dept Therapeut Chem, Cairo 12622, Egypt
[3] Natl Res Ctr, Dept Nat & Microbial Chem, Pharmaceut & Drug Ind Res Inst, Cairo 12622, Egypt
来源：
BIOCHEMISTRY AND CELL BIOLOGY | 2023年 / 101卷 / 06期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页数：25
相关论文
共 3 条
  • [1] Shedding Light on the Interaction of Human Anti-Apoptotic Bcl-2 Protein with Ligands through Biophysical and in Silico Studies
    Ramos, Joao
    Muthukumaran, Jayaraman
    Freire, Filipe
    Paquete-Ferreira, Joao
    Otrelo-Cardoso, Ana Rita
    Svergun, Dmitri
    Panjkovich, Alejandro
    Santos-Silva, Teresa
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (04):
  • [2] Inhibition of the anti-apoptotic protein BCL2 in EML4-ALK cell models as a second proposed therapeutic target for non-small cell lung cancer
    Dongo, Richard Junior Zapata
    Fontana, Diletta
    Mologni, Luca
    Castillo, Juan Enrique Faya
    Varillas, Stefany Fiorella Infante
    PLOS ONE, 2025, 20 (01):
  • [3] In Silico Computational Studies of Bioactive Secondary Metabolites from Wedelia trilobata against Anti-Apoptotic B-Cell Lymphoma-2 (Bcl-2) Protein Associated with Cancer Cell Survival and Resistance
    Gowtham, Hittanahallikoppal Gajendramurthy
    Ahmed, Faiyaz
    Anandan, Satish
    Shivakumara, C. S.
    Bilagi, Ashween
    Pradeep, Sushma
    Shivamallu, Chandan
    Shati, Ali A.
    Alfaifi, Mohammad Y.
    Elbehairi, Serag Eldin I.
    Achar, Raghu Ram
    Silina, Ekaterina
    Stupin, Victor
    Murali, Mahadevamurthy
    Kollur, Shiva Prasad
    MOLECULES, 2023, 28 (04):
1