Chemical composition and biological activities of Lonicera caprifolium L. (Caprifoliaceae) essential oil

被引:4
|
作者
Gavit, Anjali A. [1 ]
Gagrani, Manish B. [2 ]
Gurav, Shailendra S. [3 ]
Ayyanar, M. [4 ]
Beldar, Vishal G. [5 ]
Tatiya, Anilkumar U. [1 ]
Surana, Sanjay J. [1 ]
Firke, Sandip D. [1 ]
Kalaskar, Mohan G. [1 ]
机构
[1] RC Patel Inst Pharmaceut educ & Res, Dept Pharmacognosy, Shirpur, India
[2] RC Patel Inst Pharmaceut Educ & Res, Dept Pharmacol, Shirpur, India
[3] Goa Coll Pharm, Dept Pharmacognosy, Panaji, India
[4] Affiliated Bharathidasan Univ, AVV M Sri Pushpam Coll, Dept Bot, Thanjavur, India
[5] Inst Chem Technol, Dept Pharmaceut Sci & Technol, Jalna, India
关键词
Lonicera caprifolium; antioxidant; antinociceptive; wound healing; essential oil; ANTIOXIDANT ACTIVITY; EXTRACT;
D O I
10.1080/14786419.2023.2193745
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
This work aimed to investigate the chemical composition, antioxidant activity, antinociceptive effect, and wound healing activity of the Lonicera caprifolium L. flower essential oil (LCEO). Linalool (16.42%), d-limonene (9.99%), and alpha-cadinol (10.65%) were the most prevalent components of the LCEO. The LCEO revealed moderate DPPH and ABTS radical-scavenging activity. LCEO exhibited potent antinociceptive activity in acetic acid-induced writhing and hot plate-induced pain model; LCEO reduced 73.88 +/- 2.78% of writhing and significantly increased pain withdrawal latency in the mice, respectively. The LCEO also presented a potent wound healing effect, with 98.08 +/- 1.37% wound closure on the 12th day of treatment. The results of the study demonstrate antioxidant and wound healing potential with antinociceptive effect. To the best of our knowledge, this is the first report on the bioactivities of L. caprifolium L. essential oil.
引用
收藏
页码:719 / 726
页数:8
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