Selective serotonin reuptake inhibitors related bleeding risk: case report and review of literature

被引：0

作者：

Boccatonda, Andrea ^{[1
]}

D'Ardes, Damiano ^{[2
]}

Guagnano, Maria Teresa ^{[2
]}

Cipollone, Francesco ^{[2
]}

Santilli, Francesca ^{[2
]}

机构：

[1] AUSL Bologna, Bentivoglio Hosp, Internal Med, Bentivoglio, BO, Italy

[2] Ctr Aging Sci & Translat Med CESI Met, Dept Med & Aging, Chieti, Italy

来源：

EMERGENCY CARE JOURNAL | 2023年 / 19卷 / 03期

关键词：

SSRI; bleeding; platelet; thrombocytopenia; ATRIAL-FIBRILLATION; ORAL ANTICOAGULANTS; PLATELET RESPONSE; ESCITALOPRAM; CITALOPRAM; WARFARIN; IMPACT; NSAIDS; SSRIS;

D O I：

10.4081/ecj.2023.11349

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Gastrointestinal bleedings are relevant side effects in patients during anticoagulant therapy for atrial fibrillation. Direct oral anticoagulants (DOACs) are less correlated with major bleeding events than vitamin K antagonists (VKAs), but concerns are present about the relative risk of gastrointestinal bleeding. Here we report the case of a patient with atrial fibrillation and dementia on DOAC treatment who developed a SSRI-associated thrombocytopenia with subsequent life-threatening bleeding. Physicians should be aware of the possible correlation between SSRI-induced thrombocytopenia and concomitant use of anticoagulant and/or antiplatelet drugs, thus preventing life-threatening bleedings.

引用

页数：5

共 50 条

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