Palladium-Catalyzed Regioselective C-Arylation and C,N-Diarylation of N-Aryl-2,3-dihydrophthalazine-1,4-diones Using Diaryliodonium Salts

被引：3
|
作者：
Naharwal, Sushma [1 ]
Kharat, Narendra Dinkar [1 ]
Mahesha, Chikkagundagal K. [1 ]
Bajaj, Kiran [2 ]
Sakhuja, Rajeev [1 ,2 ]
机构：
[1] Birla Inst Technol & Sci, Dept Chem, Pilani 333031, Rajasthan, India
[2] Amity Univ, Amity Inst Appl Sci, Dept Chem, Noida, Uttar Pradesh, India
来源：
SYNTHESIS-STUTTGART | 2023年 / 55卷 / 21期
关键词：
arylation; biaryls; catalysis; palladium; transition metals; BIOLOGICAL EVALUATION; H ARYLATION; DESIGN; INDOLES; PHTHALAZINE; EFFICIENT;
D O I：
10.1055/a-2048-8030
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Regioselective C-arylation and C,N-diarylation in 2-aryl-2,3dihydrophthalazine-1,4-diones has been successfully accomplished with diaryliodonium salts under base-mediated slightly modified Pd catalyzed conditions. These ligand-driven transformations provided a variety of diversely decorated bi(hetero)aryls in good-to-excellent yields, while N-arylated product could be obtained under similar Pd -catalyzed conditions in the absence of a ligand.
引用
收藏
页码：3515 / 3525
页数：11
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