GUT MICROBE-DERIVED UREMIC TOXIN TRIMETHYLAMINE N-OXIDE CONTRIBUTES TO CARDIAC REMODELING IN PATIENTS ON HEMODIALYSIS

被引：0
|
作者：
Pyatchenkov, Mikhail [1 ]
Shcherbakov, Evgeniy [1 ]
机构：
[1] Mil Med Acad, Dept Nephrol & Blood Purificat, St Petersburg, Russia
来源：
NEPHROLOGY DIALYSIS TRANSPLANTATION | 2023年 / 38卷
关键词：
D O I：
暂无
中图分类号：
R3 [基础医学]; R4 [临床医学];
学科分类号：
1001 ; 1002 ; 100602 ;
摘要：
6067
引用
收藏
页码：I840 / I841
页数：2
相关论文
共 50 条
  • [1] Gut microbe-derived metabolite trimethylamine N-oxide induces cardiac hypertrophy and fibrosis
    Li, Zehua
    Wu, Zhiye
    Yan, Jianyun
    Liu, Hailin
    Liu, Qicai
    Deng, Yi
    Ou, Caiwen
    Chen, Minsheng
    LABORATORY INVESTIGATION, 2019, 99 (03) : 346 - 357
  • [2] Gut Microbe-Derived Metabolite Trimethylamine N-oxide and Risk of CKD Progression
    Cheng, Evelyn
    Lin, Ting-yun
    Hung, Szu-Chun
    JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2024, 35 (10):
  • [3] Elevated Circulating Levels of Gut Microbe-Derived Trimethylamine N-Oxide Are Associated with Systemic Sclerosis
    Ho, Karen J.
    Muhammad, Lutfiyya N.
    Khanh, Linh Ngo
    Li, Xinmin S.
    Carns, Mary
    Aren, Kathleen
    Kim, Seok-Jo
    Verma, Priyanka
    Hazen, Stanley L.
    Varga, John
    JOURNAL OF CLINICAL MEDICINE, 2024, 13 (19)
  • [4] Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis
    Yang, Wenlong
    Zhang, Shuning
    Zhu, Jianbing
    Jiang, Hao
    Jia, Daile
    Ou, Tiantong
    Qi, Zhiyong
    Zou, Yunzeng
    Qian, Juying
    Sun, Aijun
    Ge, Junbo
    JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 2019, 134 : 119 - 130
  • [5] Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation
    Kim, Seok-Jo
    Bale, Swarna
    Verma, Priyanka
    Wan, Qianqian
    Ma, Feiyang
    Gudjonsson, Johann E.
    Hazen, Stanley L.
    Harms, Paul W.
    Tsou, Pei-Suen
    Khanna, Dinesh
    Tsoi, Lam C.
    Gupta, Nilaksh
    Ho, Karen J.
    Varga, John
    ISCIENCE, 2022, 25 (07)
  • [6] Trimethylamine N-Oxide and Related Gut Microbe-Derived Metabolites and Incident Heart Failure Development in Community-Based Populations
    Tang, W. H. Wilson
    Lemaitre, Rozenn N.
    Jensen, Paul N.
    Wang, Meng
    Wang, Zeneng
    Li, Xinmin S.
    Nemet, Ina
    Lee, Yujin
    Lai, Heidi T. M.
    Otto, Marcia C. de Oliveira
    Fretts, Amanda M.
    Sotoodehnia, Nona
    Didonato, Joseph A.
    Baeckhed, Fredrik
    Psaty, Bruce M.
    Siscovick, David S.
    Budoff, Matthew J.
    Mozaffarian, Dariush
    Hazen, Stanley L.
    CIRCULATION-HEART FAILURE, 2024, 17 (08)
  • [7] A potential relationship between gut microbes and atrial fibrillation: Trimethylamine N-oxide, a gut microbe-derived metabolite, facilitates the progression of atrial fibrillation
    Yu, Lilei
    Meng, Guannan
    Huang, Bing
    Zhou, Xiaoya
    Stavrakis, Stavros
    Wang, Menglong
    Li, Xuefei
    Zhou, Liping
    Wang, Yuhong
    Wang, Meng
    Wang, Zhenya
    Deng, Jielin
    Po, Sunny S.
    Jiang, Hong
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2018, 255 : 92 - 98
  • [8] Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure
    Organ, Chelsea L.
    Otsuka, Hiroyuki
    Bhushan, Shashi
    Wang, Zeneng
    Bradley, Jessica
    Trivedi, Rishi
    Polhemus, David J.
    Tang, W. H. Wilson
    Wu, Yuping
    Hazen, Stanley L.
    Lefer, David J.
    CIRCULATION-HEART FAILURE, 2016, 9 (01)
  • [9] Simulated spaceflight-induced cardiac remodeling is modulated by gut microbial-derived trimethylamine N-oxide
    Liu, Zizhong
    Luo, Gui
    Du, Ruikai
    Kan, Guanghan
    Han, Xuan
    Zhong, Guohui
    Xing, Wenjuan
    Cui, Ying
    Sun, Weijia
    Li, Jianwei
    Li, Yuheng
    Zhao, Dingsheng
    Yuan, Xinxin
    Jin, Xiaoyan
    Han, Yanping
    Sun, Huiyuan
    Ling, Shukuan
    Li, Yingxian
    ISCIENCE, 2023, 26 (12)
  • [10] Gut microbe-derived metabolite trimethylamine N-oxide activates the cardiac autonomic nervous system and facilitates ischemia-induced ventricular arrhythmia via two different pathways
    Meng, Guannan
    Zhou, Xiaoya
    Wang, Menglong
    Zhou, Liping
    Wang, Zhenya
    Wang, Meng
    Deng, Jielin
    Wang, Yuhong
    Zhou, Zhen
    Zhang, Yifeng
    Lai, Yanqiu
    Zhang, Qianqian
    Yang, Xiaomeng
    Yu, Lilei
    Jiang, Hong
    EBIOMEDICINE, 2019, 44 : 656 - 664
12345