The association between body mass index and mortality in septic older adults

被引:0
|
作者
Li, Na [1 ]
Tian, Ling [2 ]
Zhou, Qiang [3 ]
Miao, Yuxiu [2 ]
Ma, Huashan [4 ]
机构
[1] Dongying Peoples Hosp, Dept Anesthesiol, Dongying, Shandong, Peoples R China
[2] Dongying Peoples Hosp, Dongying Hosp Shandong Prov Hosp Grp, Dept Operating theatre, Dongying, Shandong, Peoples R China
[3] Hekou Distńct Peoples Hosp, Dept Orthoped Surg, Dongying, Shandong, Peoples R China
[4] Dongying Peoples Hosp, Dongying Hosp, Dept Anesthesiol, Shandong Prov Hosp Grp, Dongying, Shandong, Peoples R China
来源
GERIATRIC NURSING | 2023年 / 54卷
关键词
Body mass index; 30-day mortality; Sepsis; Older patients; OBESITY; SEPSIS;
D O I
10.1016/j.gerinurse.2023.10.003
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: There is limited evidence on the association between body mass index (BMI) and outcomes in older adults with sepsis.Objectives: The purpose of this study was to explore the relationship between BMI and the clinical outcome in the older adults with sepsis.Methods: All older adults (age 65 or older) with sepsis were analyzed retrospectively in the Intensive Care Medical Information Mart (MIMIC)-IV database. The primary outcome was 30-day mortality. The relation-ship between BMI and 30-day mortality was estimated by multivariate logistic regression model. The inter -action and stratified analysis were performed by sex, race, renal disease, congestive heart failure (CHF), diabetes, and chronic pulmonary disease.Results: The total number of participants was 6604. After adjustment for potential covariates, there was a significant correlation between BMI and 30-day mortality. A 1 kg/m(2) increase in BMI was associated with a 3 % decrease in 30-day mortality (adjusted HR = 0.97, 95 % CI: 0.96-0.98, P < 0.001). The correlation between BMI and 30-day mortality showed a statistically significant nonlinear association with an L-shaped curve (p = 0.001). Significant interactions were observed only for sex in the stratified analyses (P = 0.001).Conclusions: In this study, it was observed that a higher BMI is linked with better survival rates among older adults suffering from sepsis, while being underweight raises the risk of mortality. Notably, male patients with a higher BMI had a lower mortality risk compared to female patients.(c) 2023 Elsevier Inc. All rights reserved.
引用
收藏
页码:199 / 204
页数:6
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