A 13-year patient journey of infant giant clival chordoma: case report and literature review

被引：1

作者：

Apps, J. ^{[1
,2
,4
]}

Gagen, R. ^{[2
,3
]}

Neumann, E. ^{[1
,2
]}

Solanki, G. ^{[4
]}

English, M. ^{[1
,2
]}

机构：

[1] Birmingham Womens & Childrens NHS Fdn Trust, Dept Oncol, Birmingham, W Midlands, England

[2] Birmingham Womens & Childrens NHS Fdn Trust, Dept Neurosurg, Birmingham, W Midlands, England

[3] Birmingham Womens & Childrens NHS Fdn Trust, Radiol Dept, Birmingham, W Midlands, England

[4] Univ Birmingham, Canc Res Clin Trials Unit, Birmingham, W Midlands, England

来源：

CHILDS NERVOUS SYSTEM | 2023年 / 39卷 / 04期

关键词：

Infant clival chordoma; Imatinib; mTOR; CHILDREN;

D O I：

10.1007/s00381-022-05749-4

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Chordomas are rare malignant bone tumours that develop from the ectopic remnants of the embryonic notochord. In contrast to adults, the majority in children under 16 present intra-cranially (63%). In 2006, we reported the youngest case of a large clival chordoma, a 15-week old baby, the second case to present without skull base involvement and the fourth case of chordoma in a patient with tuberous sclerosis (TS) Kombogiorgas (Childs Nerv Syst 22(10):1369-1374, 2006). In this report, we provide an update on this patient's journey through a range of therapeutic options and summarize an update of the literature, since 2006, for this patient group.

引用

页码：1077 / 1081

页数：5

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