Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters, aryl isothiocyanates, amines and cyclic ethers

被引：50

作者：

Lv, Yufen ^{[1
]}

Ding, Hongyu ^{[1
]}

You, Jinmao ^{[1
,2
]}

Wei, Wei ^{[1
]}

Yi, Dong ^{[3
]}

机构：

[1] Qufu Normal Univ, Key Lab Catalyt Convers & Clean Energy Univ Shando, Sch Chem & Chem Engn, Qufu 273165, Peoples R China

[2] Shaoxing Univ, Coll Chem & Chem Engn, Shaoxing 312000, Peoples R China

[3] Southwest Med Univ, Sch Pharm, Luzhou 646000, Peoples R China

来源：

CHINESE CHEMICAL LETTERS | 2024年 / 35卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Visible-light; Additive-free; Four-component reaction; S -Substituted isothioureas; DERIVATIVES; ARYLATION; GUANIDINES; IODIDES; ALKENES;

D O I：

10.1016/j.cclet.2023.109107

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An additive-free and environmentally friendly strategy has been realized for the construction of S-substituted isothioureas through visible-light-induced multicomponent reaction starting from alpha- diazoesters, aryl isothiocyanates, amines and cyclic ethers. This methodology features simple operation, mild reaction conditions, favorable functional group tolerance, easily available starting materials and high efficiency.(c) 2023 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences.

引用

页数：5

共 5 条

[1] Additive-free synthesis of S-substituted isothioureas via visible-light-induced four-component reaction of α-diazoesters, aryl isothiocyanates, amines and cyclic ethers
Yufen Lv
Hongyu Ding
Jinmao You
Wei Wei
Dong Yi
Chinese Chemical Letters, 2024, 35 (02) : 443 - 447
[2] Visible-Light-Induced Synthesis of Thioethers through Three-Component Reactions of a-Diazoesters, Thiols, and Cyclic Ethers
Lv, Yufen
Wang, Zhiwei
Hao, Jindong
Zhao, Xiaohui
Wei, Wei
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2023, 12 (08)
[3] Visible-light-induced oxidant/additive-free atom-economic synthesis of multifunctionalized cyclopropanes via energy transfer
Gore, Babasaheb Sopan
Wang, Jeh-Jeng
CHEMICAL COMMUNICATIONS, 2023, 59 (39) : 5878 - 5881
[4] Transition-metal-, oxidant- and additive-free multi-component synthesis of alkyl heteroaryl BCPs enabled by visible-light-induced phosphine-catalyzed halogen-atom transfer
Xu, Jun
Hong, Yu
Xu, Ruiyuan
Wang, Yuxin
Guo, Yirui
Shen, Jiabin
Zhao, Yuxuan
Li, Wanmei
ORGANIC CHEMISTRY FRONTIERS, 2024, 11 (21): : 6166 - 6176
[5] Sulfur Catalyzed Metal- and Solvent-Free ABB'C Four-Component Synthesis of N-Arylidene-2-aryl-imidazo[1-2-a]azin-3-amines via Strecker Reaction
Pavithra, Thangavel
Devi, E. Sankari
Nagarajan, Subbiah
Sridharan, Vellaisamy
Maheswari, C. Uma
CHEMISTRYSELECT, 2021, 6 (14): : 3548 - 3552

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