INHIBITION OF PDE2 RESCUES COGNITIVE DEFICITS IN AD MICE AFTER TBI

被引：0
|
作者：
Mastromatteo-Alberga, Patrizzia [1 ]
Placeres-Uray, Fabiola [1 ]
Torres, Maria Dominguez [1 ]
Xu, Ying [2 ]
Atkins, Coleen [1 ]
机构：
[1] Univ Miami, Miller Sch Med, Miami, FL 33136 USA
[2] Rutgers State Univ, Newark, NJ USA
来源：
JOURNAL OF NEUROTRAUMA | 2023年 / 40卷 / 15-16期
关键词：
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
P04.101
引用
收藏
页码：A64 / A65
页数：2
相关论文
共 50 条
  • [1] PDE2 inhibition: Potential for the treatment of cognitive disorders
    Gomez, Laurent
    Breitenbucher, J. Guy
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (24) : 6522 - 6527
  • [2] Baicalein Ameliorates Aβ-Induced Memory Deficits and Neuronal Atrophy via Inhibition of PDE2 and PDE4
    Shi, Jing
    Li, Yuanyuan
    Zhang, Yi
    Chen, Jie
    Gao, Jianqing
    Zhang, Tianyuan
    Shang, Xiaoguang
    Zhang, Xiangnan
    FRONTIERS IN PHARMACOLOGY, 2021, 12
  • [3] PDE2 and 5 inhibitors and cognitive function
    Prickaerts, J.
    Rutten, K.
    Reneerkens, O.
    Sik, A.
    Blokland, A.
    Steinbusch, H. W. M.
    BEHAVIOURAL PHARMACOLOGY, 2007, 18 : S8 - S8
  • [4] MECHANISMS OF CHRONIC COGNITIVE DEFICITS AFTER TBI
    McGuire, Jennifer
    DePasquale, Erica
    Asch, Ruth
    Anwar, Fatima
    Koene, Rachel
    McCullumsmith, Robert
    JOURNAL OF NEUROTRAUMA, 2016, 33 (13) : A59 - A59
  • [5] Inhibition of PDE2 and PDE4 synergistically improves memory consolidation processes
    Paes, Dean
    Xie, Keqiang
    Wheeler, Damian G.
    Zook, Douglas
    Prickaerts, Jos
    Peters, Marco
    NEUROPHARMACOLOGY, 2021, 184
  • [6] Inhibition of PDE2 and PDE5: Effects on object recognition and object location memory
    Reneerkens, O. A. H.
    Rutten, K.
    Sik, A.
    Steinbusch, H. W. M.
    Blokland, A.
    Prickaerts, J.
    BEHAVIOURAL PHARMACOLOGY, 2007, 18 : S100 - S100
  • [7] Restoration of cognitive deficits after statin feeding in TBI
    Chauhan, Neelima B.
    Gatto, Rodolfo
    RESTORATIVE NEUROLOGY AND NEUROSCIENCE, 2011, 29 (01) : 23 - 34
  • [8] Inhibition of PDE2, PDE5 and PDE10: Effects on short-term memory
    Reneerkens, O. A. H.
    Rutten, K.
    Sik, A.
    Blokland, A.
    Steckler, T.
    Steinbusch, H. W. M.
    Prickaerts, J.
    BEHAVIOURAL PHARMACOLOGY, 2008, 19 (5-6): : 670 - 670
  • [9] Alleviation of neuronal oxidative stress by thioredoxin through PDE2 inhibition
    Klabnik, Jonathan
    O'Donnell, James
    FASEB JOURNAL, 2014, 28 (01):
  • [10] PDE2 and PDE10, but not PDE5, inhibition affect basic auditory information processing in rats
    Reneerkens, O. A. H.
    Sambeth, A.
    Blokland, A.
    Prickaerts, J.
    BEHAVIOURAL BRAIN RESEARCH, 2013, 250 : 251 - 256
12345