A fluid biomarker accurately detects tau aggregate pathology in Alzheimer's disease

被引:0
|
作者
Bateman, Randall J. [1 ]
Horie, Kanta [1 ]
Hansson, Oskar [2 ]
机构
[1] Washington Univ, Sch Med, St Louis, MO 63130 USA
[2] Lund Univ, Lund, Sweden
关键词
D O I
10.1038/s41591-023-02468-4
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cost-effective fluid biomarkers for tau aggregate pathology would improve the diagnostic and prognostic work-up of Alzheimer’s disease and facilitate the discovery of anti-tau therapies. We identified MTBR-tau243 as a specific marker for tau aggregate pathology that could be implemented in clinical practice and trials.
引用
收藏
页码:1912 / 1913
页数:2
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