Pharmacological activity of an AAV in vivo expressed IL-33 neutralising agent in an Alternaria alternata extract induced model of acute lung inflammation in mice

被引：0

作者：

Corkill, Dominic ^{[1
]}

Dodd, Alison ^{[1
]}

Nuccitelli, Annalisa ^{[2
]}

Chandran, Jayanth ^{[2
]}

Cohen, Suzanne ^{[3
]}

Dobson, Claire ^{[4
]}

机构：

[1] AstraZeneca, Biosci Vivo, Resp & Immunol R&I, BioPharmaceut R&D,Res & Early Dev, Cambridge, England

[2] AstraZeneca, Res & Early Dev, ADPE, Cambridge, England

[3] AstraZeneca, Biosci Asthma & Skin Immun, Res & Early Dev, Resp & Immunol R&I,BioPharmaceut R&D, Cambridge, England

[4] AstraZeneca, Discovery Sci, Cambridge, England

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 2023年 / 180卷

关键词：

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

P0086

引用

页码：430 / 431

页数：2

共 14 条

[1] Differential protease content of mast cells and the processing of IL-33 in Alternaria alternata induced allergic airway inflammation in mice
Krysko, Olga
Korsakova, Darya
Teufelberger, Andrea
De Meyer, Amse
Steels, Jill
De Ruyck, Natalie
van Ovost, Judith
Van Nevel, Sharon
Holtappels, Gabriele
Coppieters, Frauke
Ivanchenko, Mikhail
Braun, Harald
Vedunova, Maria
Krysko, Dmitri V. V.
Bachert, Claus
FRONTIERS IN IMMUNOLOGY, 2023, 14
[2] Characterisation of endogenous IL-33 using a model of Alternaria-induced pulmonary inflammation
Cohen, Suzanne
Majithiya, Jayesh
Davis, Nicola
Scott, Ian
Robinson, Laura
Lewis, Arthur
Prior, Andrew
Rebelatto, Marlon
Corkill, Dominic
Sleeman, Matthew
May, Richard
EUROPEAN RESPIRATORY JOURNAL, 2012, 40
[3] The Role of IL-33 on LPS-Induced Acute Lung Injury in Mice
Yaping Zhang
Ran Lv
Xuming Hu
Li Jiang
Dongju Xiao
Yv Sun
Jinning Zhao
Qi Bao
Junran Xie
Inflammation, 2017, 40 : 285 - 294
[4] The Role of IL-33 on LPS-Induced Acute Lung Injury in Mice
Zhang, Yaping
Lv, Ran
Hu, Xuming
Jiang, Li
Xiao, Dongju
Sun, Yv
Zhao, Jinning
Bao, Qi
Xie, Junran
INFLAMMATION, 2017, 40 (01) : 285 - 294
[5] IL-33 affects cytokine profile in psoriasis inflammation in imiquimod-induced psoriasis model mice
Tsuda, H.
Komine, M.
Hioki, T.
Nakae, S.
Ohtsuki, M.
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2019, 139 (05) : S12 - S12
[6] Osthole attenuates ovalbumin-induced lung inflammation via the inhibition of IL-33/ST2 signaling in asthmatic mice
Yang, Qingqing
Kong, Lingwen
Huang, Weiling
Mohammadtursun, Nabijan
Li, Xiumin
Wang, Guifang
Wang, Lixin
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2020, 46 (04) : 1389 - 1398
[7] Expression Of Lung Human Interleukin-32γ In Mice Enhances Allergen-Induced Airway Hyperresponsiveness And Inflammation Through Upregulation Of Il-33
Takeda, K.
Kim, S. -H.
Bai, X.
Kim, S.
Chan, E. D.
Gelfand, E. W.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2015, 191
[8] Respiratory syncytial virus upregulates IL-33 expression in mouse model of virus-induced inflammation exacerbation in OVA-sensitized mice and in asthmatic subjects
Nikonova, Alexandra
Shilovskiy, Igor
Galitskaya, Mariola
Sokolova, Alina
Sundukova, Maria
Dmitrieva-Posocco, Oksana
Mitin, Aleksandr
Komogorova, Viktoria
Litvina, Marina
Sharova, Nina
Zhernov, Yury
Kudlay, Dmitry
Dvornikov, Anton
Kurbacheva, Oksana
Khaitov, Rakhim
Khaitov, Musa
CYTOKINE, 2021, 138
[9] Fallopia japonica Root Extract Ameliorates Ovalbumin-Induced Airway Inflammation in a CARAS Mouse Model by Modulating the IL-33/TSLP/NF-κB Signaling Pathway
Jin, Juan
Fan, Yan Jing
Nguyen, Thi Van
Yu, Zhen Nan
Song, Chang Ho
Lee, So-Yong
Shin, Hee Soon
Chai, Ok Hee
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (15)
[10] IL-33 Deficiency Attenuates Lung Inflammation by Inducing Th17 Response and Impacting the Th17/Treg Balance in LPS-Induced ARDS Mice via Dendritic Cells
Cheng, Li
Jiao, Yang
Jiang, Wei
Zhang, Xin
Zhang, Liping
Jia, Gongwei
JOURNAL OF IMMUNOLOGY RESEARCH, 2022, 2022

← 1 2 →