. Semi-unification is the combination of first-order unification and first-order matching. The undecidability of semi-unification has been proven by Kfoury, Tiuryn, and Urzyczyn in the 1990s by Turing reduction from Turing machine immortality (existence of a diverging configuration). The particular Turing reduction is intricate, uses noncomputational principles, and involves various intermediate models of computation. The present work gives a constructive many-one reduction from the Turing machine halting problem to semi-unification. This establishes RE-completeness of semi-unification under many-one reductions. Computability of the reduction function, constructivity of the argument, and correctness of the argument is witnessed by an axiom-free mechanization in the Coq proof assistant. Arguably, this serves as comprehensive, precise, and surveyable evidence for the result at hand. The mechanization is incorporated into the existing, wellmaintained Coq library of undecidability proofs. Notably, a variant of Hoop er's argument for the undecidability of Turing machine immortality is part of the mechanization.