Systematic review of automated sleep apnea detection based on physiological signal data using deep learning algorithm: a meta-analysis approach

Sleep apnea (SLA) is a respiratory-related sleep disorder that affects a major proportion of the population. The gold standard in sleep testing, polysomnography, is costly, inconvenient, and unpleasant, and it requires a skilled professional to score. Multiple researchers have suggested and developed automated scoring processes with less detectors and automated classification algorithms to resolve these problems. An automatic detection system will allow for a high diagnosis rate and the analysis of additional patients. Deep learning (DL) is achieving high priority due to the availability of databases and recently developed methods. As the most up-and-coming technique for classification and generative tasks, DL has shown its significant potential in 2-dimensional clinical image processing studies. However, physiological information collected as 1-dimensional data has yet to be effectively extracted from this new approach to achieve the needed medical goals. So, in this study, we review the most recent studies in the field of DL applied to physiological data based on pulse oxygen saturation, electrocardiogram, airflow, and sound signal. A total of 47 articles from different journals and publishing houses that were published between 2012 and 2022 were identified. The primary objective of this work is to perform a comprehensive analysis to analyze, classify, and compare the main characteristics of deep-learning algorithms applied in physiological data processing for SLA detection. Overall, our analysis provides comprehensive and detailed information for researchers looking to add to this field. The data input source, objective, DL network, training framework, and database references are the critical factors of the DL approach examined. These are the most critical variables that influence system performance. We categorized the relevant research studies in physiological sensor data analysis using the DL approach based on (1) Physiological sensor data aspects, like signal types, sampling frequency, and window size; and (2) DL model perspectives, such as learning structure and input data types.