Telemedicine holds potential to improve access to gender-affirming care for gender-diverse youth (GDY), but little is known about youth's perspectives regarding its use. An online, cross-sectional survey was completed by 12-17-yearGDY after a telemedicine gender clinic visit. Participants' mean age was 15.6 years. A majority were satisfied with telemedicine and willing to use it in the future. Most GDY preferred in-person visits for their first gender care visit, with fewer preferring in-person for follow-up visits. Three key themes emerged from the open ended comments: (1) benefits of telemedicine including saving time and feeling safe; (2) usability of telemedicine such as privacy concerns and technological difficulties; and (3) telemedicine acceptability, which included comfort, impact on anxiety, camera use, and patient preference. Despite their preference for in-person visits, a majority of GDY were satisfied and comfortable with telemedicine, and expressed their interest in continuing to have telemedicine as an option for care.