Within the context of this article, an analysis of quality management systems -QMS and quality tools and their application in small and medium-sized companies located in Cundinamarca, Colombia and Guanajuato, Mexico, is seen. The investigative scope is descriptive based on the theoretical variables competence and innovation management, the research design is quasi-experimental, it is of a mixed type, The information was obtained through a Delphi-type survey, within which the application of quality experts from 26 companies in Mexico and Colombia was obtained. of quality experts from 26 companies in Mexico and Colombia. In the information that was analyzed, it was found that the quality management systems serve the entities to improve the competitive and productive level, making products and providing services taking into account the quality processes together with the use of quality tools in each process and procedure which facilitates a company to be certified with the ISO Standard, generating greater credibility and trust towards clients in local, national and international contexts in the countries of Colombia and Mexico with innovative management, enhancing organizational competitiveness in SMEs.