IL-22: Immunity's bittersweet symphony

被引：2
|
作者：
Duan, Jinzhi [1 ]
Matute, Juan D. [1 ,2 ]
Blumberg, Richard S. [1 ]
机构：
[1] Harvard Med Sch, Brigham & Womens Hosp, Dept Med, Div Gastroenterol, Boston, MA 02115 USA
[2] Harvard Med Sch, Massachusetts Gen Hosp, Dept Pediat, Div Neonatol & Newborn Med, Boston, MA USA
来源：
JOURNAL OF EXPERIMENTAL MEDICINE | 2023年 / 220卷 / 11期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1084/jem.20231210
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Epithelial cells play a crucial role in barrier defense. Here, Moniruzzaman et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20230106) discovered that interleukin-22 (IL-22) represses MHC class II expression by epithelial cells with an opposite impact on chronic inflammatory disease and viral infection.
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页数：3
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